hlsn，电气标识？
电气符号大全（Electrical symbols Daquan），包含继电器 KJ2、电流继电器 KA LJ、负序电流继电器 KAN FLJ等。
中文名
电气符号大全
外文名
Electrical symbols Daquan
电气符号
1 继电器 KJ
2 电流继电器 KA LJ
3 负序电流继电器 KAN FLJ
4 零序电流继电器 KAZ LLJ
5 电压继电器 KV YJ
6 正序电压继电器 KVP ZYJ
7 负序电压继电器 KVN FYJ
8 零序电压继电器 KVZ LYJ
9 时间继电器 KT SJ
10 功率继电器 KP GJ
11 差动继电器 KD CJ
12 信号继电器 KS XJ
13 信号冲击继电器 KAI XMJ
14 继电器 KC ZJ
15 热继电器 KR RJ
16 阻抗继电器 KI ZKJ
17 温度继电器 KTP WJ
18 瓦斯继电器 KG WSJ
19 合闸继电器 KCR或KON HJ
20 跳闸继电器 KTR TJ
21 合闸 继电器 KCP HWJ
22 跳闸 继电器 KTP TWJ
23 电源监视继电器 KVS JJ
24 压力监视继电器 KVP YJJ
25 电压 继电器 KVM YZJ
26 事故信号 继电器 KCA SXJ
27 继电保护跳闸出口继电器 KOU BCJ
28 手动合闸继电器 KCRM SHJ
29 手动跳闸继电器 KTPM STJ
30 加速继电器 KAC或KCL JSJ
31 复归继电器 KPE FJ
32 闭锁继电器 KLA或KCB BSJ
33 同期检查继电器 KSY TJJ
34 自动准同期装置 ASA ZZQ
35 自动重合闸装置 ARE ZCJ
36 自动励磁调节装置 AVR或AAVR ZTL
37 备用电源自动投入装置 AATS或RSAD BZT
38 按扭 SB AN
39 合闸按扭 SBC HA
40 跳闸按扭 SBT TA
41 复归按扭 SBre或SBR FA
42 试验按扭 SBte YA
43 紧急停机按扭 SBes JTA
44 起动按扭 SBst QA
45 自保持按扭 SBhs BA
46 停止按扭 SBss
47 控制开关 SAC KK
48 转换开关 SAH或SA ZK
49 测量转换开关 SAM CK
50 同期转换开关 SAS TK
51 自动同期转换开关 2SASC DTK
52 手动同期转换开关 1SASC STK
53 自同期转换开关 SSA2 ZTK
54 自动开关 QA
55 刀开关 QK或SN DK
56 熔断器 FU RD
57 快速熔断器 FUhs RDS
58 闭锁开关 SAL BK
59 信号灯 HL XD
60 光字牌 HL或HP GP
61 警铃 HAB或HA JL
62 合闸接触器 KMC HC
63 接触器 KM C
64 合闸线圈 Yon或LC HQ
65 跳闸线圈 Yoff或LT TQ
66 插座 XS
67 插头 XP
68 端子排 XT
69 测试端子 XE
70 连接片 XB LP
71 蓄电池 GB XDC
72 压力变送器 BP YB
73 温度变送器 BT WDB
74 电钟 PT
75 电流表 PA
76 电压表 PV
77 电度表 PJ
78 有功功率表 PPA
79 无功功率表 PPR
80 同期表 S
81 频率表 PF
82 电容器 C
83 灭磁电阻 RFS或Rfd Rmc
84 分流器 RW
85 热电阻 RT
86 电位器 RP
87 电感（电抗）线圈 L
88 电流互感器 TA CT或LH
89 电压互感器 TV PT或YH
10KV电压互感器 TV SYH
35KV电压互感器 TV UYH
110KV电压互感器 TV YYH
90 断路器 QF DL
91 隔离开关 QS G
92 电力变压器 TM B
93 同步发电机 GS TF
94 交流电动机 MA JD
95 直流电动机 MD ZD
96 电压互感器二次回路小母线
97 同期电压小母线（待并） WST或WVB TQMa,TQMb
98 同期电压小母线（运行） WOS`或WVBn TQM`a,TQM`b
99 准同期合闸小母线 1WSC,2WSC,3WSC，1WPO,2WPO,3WPO 1THM,2THM,3THM
100 控制电源小母线 +WC,-WC +KM,-KM
101 信号电源小母线 +WS,-WS +XM,-XM
102 合闸电源小母线 +WON,-WON +HM,-HM
103 事故信号小母线 WFA SYM
104 零序电压小母线 WVBz[1
如何学习音标？
音标是学习英语的第一步，想要学好音标需要认识音标、会读音标，这样以后才能认识单词。在学习音标前，我们要先知道国际音标有48个，元音有20个，辅音有28个，元音又分为单元音和双元音，单元音有12个，双元音有8个。
音标数目
在上表中，我们可以看到音标有48个，现在我们常说的国际音标也是48个。
可以点击下面链接学习音标。
《【48个英语音标示范读音-哔哩哔哩】 https://b23.tv/mt9vVaK》
元音部分
辅音部分
音标的分类
最实用的分类方式是：元音=长元音+短元音+双元音；辅音=清辅音+浊辅音。
英语一共有48个国际音标，包括20个元音，28个辅音。
20个元音包括5个长元音：/i:/、/ɜ:/、/u:/、/a:/、/ɔ:/；
7个短元音：[i] [ə] [ɔ] [u] [ʌ] [e] [æ]；
8个双元音：/eɪ、/aɪ/、/ɔɪ/、/ɪə/、/eə/、/ʊə/、/əʊ/、/aʊ/；
注意：
1、长元音顾名思义就是发的音比较长而饱满；短元音则发的音比较短而急；
2、双元音就是两个单元音拼在一起，成为组合音。双元音发音的特点是前面的单元音发音长，后面的发音比较短。
28个辅音包括：轻辅音/p/ /t/ /k/ /f/ /θ/ /s/ /ʃ/ /ts/ /tʃ/ /tr/ /h/
浊辅音 /b/ /d/ /g/ /v/ /ð/ /z/ /ʒ/ /dz/ /dʒ/ /dr/ /r/
鼻音 /m/ /n/ /ŋ/
半元音 /j/ /w/
边音 /ǀ/
发音技巧
长元音
点击这个视频学习长元音发音。《【元音音标（长元音）-哔哩哔哩】 https://b23.tv/xz9mOz3》
5个长元音/i:/、/ɜ:/、/u:/、/a:/、/ɔ:/发音技巧。
（1）/i:/发音技巧：
发音时舌尖抵下齿，口形扁平。在发音的时候要尽量拉长，就像古人喝醉酒以后吟诗的感觉。
单词举例：bee [biː] n. 蜜蜂；see [siː] v. 看见，参看
（2）/ɜ:/发音技巧：
/ɜ:/是长元音，近似于北京腔的“儿”话音，如“花儿”的“儿”。发好这个音，关键在于卷舌！
单词举例：shirt [ʃə:t] n. 衬衫,男士衬衫；nurse [nə:s] n. 护士,保姆
（3）/u:/发音技巧
发这个音时双唇用力向前突出，有点像拉长了音说“乌”，但要注意，“乌”的口形较扁。
单词举例：moon [mu:n] n. 月球,月亮；room [ruːm] n. 房间,空间
（4）/a:/发音技巧
发音时口张大，双唇稍收圆。发音时可以照着镜子，说“啊”，看看嘴巴张得够不够大，记得要将嘴巴尽量张大。
单词举例：ask [a:sk] v. 问,询问； far [fa:r] adj. 远的
（5）/ɔ:/发音技巧
发这个音时，双唇稍稍收圆，并向前突出，发音接近于汉语“嗷”。这是个长元音，记住：长元音一定要拉长，发出来才好听。
单词举例：door [dɔ:r] n. 门； short [ʃɔ:t] adj. 短的
短元音
点击这个视频学习短元音发音。《【【英语音标7个短元音/ʌ/ /ɒ/ /ə/ /ɪ/ /ʊ/ /e/ /æ/怎么读？】-哔哩哔哩】 https://b23.tv/fo9Bd5E》
7个短元音：/i/、/ə/、 /ɔ/、/u/、/ʌ/、/e/、/æ/
（1）/i/发音技巧
它是个短元音，发音要短促而轻快。
单词举例：big [bɪɡ] adj. 大的,庞大的；Fit [fit] v. 合身,适合于
（2）/ə/发音技巧
发音时舌身平放，双唇扁平。发这个音时不用卷舌。
单词举例：teacher [ˈtiːtʃə] n. 老师,教师； mother [ˈmʌðə] n. 母亲
（3）/ɔ/ 发音技巧
这是一个短元音，发音一定要短，发音比/ɔ:/短一些，双唇稍稍收圆，并向前突出。
单词举例：dog [dɔg] n.狗,家伙；hot [hɔt] adj. 热的,辣的
（4）/u/ 发音技巧
发音时双唇收圆，稍突出。就像发汉语中的“乌”，但没发完就给打断了一样。
单词举例：book [bʊk] n. 书,卷；cook [kʊk] vt. 烹调,煮
（5）/ʌ/ 发音技巧
发音时舌尖和舌端两侧轻触下齿，唇形稍扁，开口度较大。这个发音有点像发“啊”音时突然被谁卡住了脖子的感觉。
单词举例：brother['brʌðə(r)] n. 哥哥，弟弟；mother [ˈmʌðə] n. 母亲
（6）/e/发音技巧
发音时舌尖抵下齿，舌前部稍抬起，上下嘴张开的角度大约呈“45度”，同时发出声音。
单词举例：leg [leg] v. n. 腿,支柱； desk [desk] n. 书桌
（7）/æ/发音技巧
发音时，双唇向两边平伸，张开嘴，嘴唇放松逐渐压低舌头7和下颚，尽可能夸张。
单词举例：bad [bæd] ：adj. 坏的,不好的；cat [kæt] ：n. 猫，猫科动物
双元音
点击这个视频学习双元音发音。《【【英语基础】英语国际音标-8个双元音的发音-哔哩哔哩】 https://b23.tv/VQsPDdl》
8个双元音发音技巧：/eɪ/、/aɪ/、/ɔɪ/、/ɪə/、/eə/、/ʊə/、/əʊ/、/aʊ/
（1）/eɪ/发音技巧
该音是个双元音，发音时双唇稍扁，口形从半开到合。类似于英文字母“A”。
单词举例：say[sei] v.说；delay[diˈlei] n. 延迟
（2）/aɪ/发音技巧
发此音的关键是要把/a/音发足，接近于英文字母中的“I”。
单词举例：ice [ais] n. 冰，雪糕；side [said] n. 面，边
（3）/ɔɪ/发音技巧
发音时双唇从圆到扁，口形从开到合。接近于汉语发音“奥一”。
单词举例：oil [ɔil] n. 油，石油；noise [nɔɪz] n. 噪音，嘈杂声
（4）/ɪə/发音技巧
发声时，由第一个音[i]向[ə]集中，接近于汉语发音“一呃”。
单词举例：fear [fɪər] ：n. 害怕，可能性；dear [dɪər] ：adj. 亲爱的
（5）/eə/发音技巧
接近于汉语发音“哎呃”。
单词举例：bear [bɛə] ：n. 熊；wear [wɛə] ：vt. 穿着
（6）/ʊə/发音技巧
第一个是“短乌音”/u/，第二个是/ə/。类似于汉语发音“屋呃”。
单词举例：sure [ʃʊər] adj. 确信的，确实的；pure [pjʊər] adj. 纯的； 单纯的
（7）/əʊ/发音技巧
舌位由半低到高，口形由半开到小。接近于汉语发音“呃屋”。
单词举例： flow [fləu] ：vi. 流；glow [ɡləʊ] ：vi. 发光，灼热
（8）/aʊ/发音技巧
由第一个音向第二个音滑动，接近于汉语发音“啊屋”。
单词举例：cow [kaʊ] n. 奶牛，乳牛；hour [aʊər] n. 小时，钟头
辅音
点击这个视频学习辅音发音。《【英语音标（辅音部分），发音规则与技巧！美式发音，地道口语！清辅音，浊辅音！初级，零基础，欢迎新手！-哔哩哔哩】 https://b23.tv/dCgZVAA》
11个清辅音 /p/ /t/ /k/ /f/ /θ/ /s/ /ʃ/ /ts/ /tʃ/ /tr/ /h/
11个浊辅音 /b/ /d/ /g/ /v/ /ð/ /z/ /ʒ/ /dz/ /dʒ/ /dr/ /r/
注意：
清辅音：发音时送气，声带不颤动（颤不颤用手放在喉咙上就知道了）
浊辅音：发音时不送气(拿张纸放在嘴前，纸没有被吹开)，声带颤动。
（1）/p/ /b/谐音分别为“普”、“卜”，都省去韵母成分
发音方法：/p/是清辅音，声带不振动；/b/是浊辅音，声带振动。
单词举例：/p/：pen [pen] n.钢笔；pin [pin] n.大头针
/b/：bike [baik] n.自行车；beg [beg] v.乞求
（2）/t/ /d/分别谐音“特”、“得”。
发音方法：/t/是清辅音，声带不振动；/d/是浊辅音，声带振动。
单词举例：/t/ ：ten [ten] num； test [test] n. 试验, 考验
/d/： student [ˈstudnt] n.学生； date [deɪt] n.日期、日子、约见时间 v.注明日期、写上日期
（3）/k/ /g/分别谐音“可”、“嗝”。
发音方法：发音时舌后部隆起紧贴软颚，憋住气，然后突然分开，气流送出口腔，形成爆破音。/k/是清辅音，声带不要振动；/g/是浊辅音，声带需要振动。
单词举例：/k/ ：kite [kait] n. 风筝；cake [keɪk] n. 蛋糕
/g/： glove [ɡlʌv] n. 手套；girl [ɡə:l] n. 女孩
（4）/f/ /v/
/f/谐音“府”，/v/就是北方人把W读成V那种感觉。
发音方法：发音前，上齿咬住下嘴唇，然后使气流由唇齿间的缝隙中通过，从而引起摩擦。
/f/是清辅音，发音时声带不震动；/v/是浊辅音，发音时声带振动。
单词举例：/f/：flower ['flaʊər] n. 花；fly [flai] vi.飞, 飞行
/v/：love [lʌv] v. 爱；seven [ˈsevən] num. 七
(5)/θ/ /ð/ 牙齿轻咬舌尖发出的音
发音方法：发音时，舌尖微微伸出，置于上下门齿之间，舌尖和下齿之间的气流通道非常窄小，气流从舌齿间的窄缝中通过。/θ/是清辅音，发音时声带不振动；/ð/是浊辅音，发音时声带振动。
单词举例：/θ/：three [θri:] num. 三； throw [θrəʊ] vi. 投掷
/ð/：this [ðɪs] pron. 这,这个，这里； mother [ˈmʌðə(r)] n. 母亲
(6)/s/ 谐音“丝”，/z/“zi”
发音方法：发音时舌端靠近齿龈，气流由舌端齿龈间送出。/s/是清辅音，声带不振动；/z/是浊浦音，声带振动。
单词举例：/s/：school [sku:l] n. 学校，学院；bus [bʌs] n. 公共汽车
/z/：please [pli:z] int.请；zoo [zu:] n.动物园
(7)/ts/ /dz/分别谐音“次”、“自”
发音方法：舌端先贴住上齿龈，堵住气流，气流送出口腔。/ts/是清辅音，声带不振动，/dz/是浊辅音，声带振动。
单词举例：/ts/：cats [kæts] n. 猫( cat的名词复数 )；hats [hæts] n. 帽子( hat的名词复数 )
/dz/：hands [hændz] n.手；lands [lændz] n.陆地
(8)/tr/ /dr/分别谐音“戳”、“捉”
发音方法：舌尖贴齿龈后部，气流冲破阻碍发出短促的/t/后立即发/r/。/tr/是清辅音，声带不振动；/dr/是浊辅音，声带振动。
单词举例：/tr/ : tree [tri:] n. 树，木料；try [traɪ] vt.& vi. 试图
/dr/：dress [dres] n.连衣裙；drink [drɪŋk] v.喝酒
(9)/∫/ /ʒ/分别谐音“诗”、“日”
发音方法：/∫/是清辅音，声带不振动；/ʒ/是浊辅音，声带振动。
单词举例：/∫/：English [ˈɪŋglɪʃ] adj. 英格兰的； 英国的；rubbish [ˈrʌbɪʃ] n. 垃圾；
/ʒ/：pleasure [ˈpleʒə] n.快乐，愉快；casual [ˈkæʒuəl] adj意外的，偶然的
（10）/t∫/ /dʒ/分别谐音“吃”、“之”
发音方法：发音时舌身抬高，舌端抵上齿龈后部，气流通过时发出破擦音。/t∫/是清辅音，声带不振动；/dʒ/是浊辅音，声带振动。
单词举例：/t∫/： chalk [tʃɔ:k] n. 粉笔；chair [tʃeər] n. 椅子
/dʒ/：page [peɪdʒ] n.页 ；age [eɪdʒ] n.年龄
(11)/h/ /r/分别谐音“呵”、“若”，省去韵母成分。
发音方法：
发/h/这个音时，嘴半开，气流从口腔不受阻碍而出，声带不振动，清辅音。
发/r/这个音时，舌端上卷，靠近上齿龈附近，嘴唇张开并保持略圆状态，气流从口腔涌出，声带振动，属于浊辅音。
单词举例: /h/： hair [heə(r)] n.头发；hate [heɪt] v.恨，厌恶
/r/： sorry ['sɒrɪ] v.对不起 ；write [raɪt] v.写
鼻音
点击这个视频学习鼻音发音。《【（21）鼻音 m n ŋ | 英语音标发音口型示范 | 美式发音-哔哩哔哩】 https://b23.tv/8P1jfXx》
(1)/m/谐音“恩”
发音方法：双唇紧闭，软腭下垂，气流从鼻腔发出，声带震动。闭口音。
单词举例：major [ˈmeɪdʒə(r)] adj.主要的；time [taɪm] n.时间
(2)/n/谐音“呢”
发音方法：舌尖顶住上齿龈，形成阻碍，气流从鼻腔发出，同时声带震动，开口音。
单词举例：nice [naɪc] adj.漂亮的；funny [ˈfʌni] adj.有趣的
(3)/ŋ/谐音“英”，省去声母部分
发音方法：发音时气流从鼻腔涌出，声带振动。
单词举例： think [θɪŋk] v.想；angel [ˈeɪndʒl] n.天使
边音
点击这个视频学习边音发音。《【真正的国际音标-边音 Lateral-哔哩哔哩】 https://b23.tv/G9C7X9F》
/l/谐音“里”
发音方法：舌尖顶住上齿龈，发音时气流从舌面的两侧通过，声带保持震动，属于浊辅音。
单词举例：light [laɪt] n.光线 ；ball [bɔ:l] n.球
半元音
点击这个视频学习半元音发音。《【BBC英语 其他辅音 半元音'w'的发音 与'v'的区别 国际音标发音｜Pronunciation Tips 34 - Other Consonant-哔哩哔哩】 https://b23.tv/fC2pYDl》
/j/谐音“耶”
发音方法：发音时声带震动，气流口腔发出。浊辅音，发音口型类似/ i/.
单词举例：ye [jes] adv.是的；young [jʌŋ] adj.年轻的
/w/谐音“屋”
发音方法：嘴唇张开到刚好可以含住一根吸管的程度，并向前微噘起，但上齿不能接触下唇,立刻滑向其后的元音。
单词举例：wish [wɪʃ] ：v. 希望； which [wɪtʃ] ：pron. 哪一个
学习步骤
抄写
抄写音标，并了解音标特点。
对音标的基本认知
1、区别长短音带“：”的音标发音相对较长不带“：”的音标发音相对较短。
2、区别清辅音和浊辅音核心区别：清辅音声带不震动，浊辅音声带振动。
模仿练习
找合适的视频学习学习跟读。例如b站上《【赖世雄48个英语音标朗读示范，美音英音对照版-哔哩哔哩】 【https://b23.tv/sHYQFZ3】》、《【李咏梅老师英语（音标部分）——最牛的初中英语老师！没有之一！李咏梅国际音标 （完整版发音篇）-哔哩哔哩】 https://b23.tv/U1pmjNE》、《【纯正英式发音】这是BBC出品的到现在为止最棒的英语发音教程（完整版）-哔哩哔哩】 https://b23.tv/gZzDKl5》，以上几个视频都非常不错，详细讲解每个音标的读法。注意视频一定至少跟读5遍，才能确保你的学习效果。
也可以通过下面这个视频观察发音口型的变化。
《【48个英语音标示范读音-哔哩哔哩】 https://b23.tv/mt9vVaK》
1、模仿练习，学习国际音标的发音，要注意观察老师的口型，观察发音部位的变化，主动模仿发音，初学可以对着镜子模仿练习，特别是元音发音的舌位高低，口腔开口度大小与音色关系十分密切，可以通过镜子观察口型上的区别，观察舌尖、舌面、舌叶的活动情况，比如u和o、i和e、e和ε等等，掌握准确口腔开口度，对于准确发音具有非常重要的意义。
2、听音训练:学习国际音标需要认识48个音标，通过反反复复的听力练习，达到强化记忆。听音训练，如果有条件，可以多听老师朗读音标，也可以使用录音带反复听音，本课件中的每个音素，都可以循环倾听，强化记忆。
3、多动口，动口是加强实践的关键和核心，听音也好，模仿也好，比较也好，最终要归结到自己发音这一目标上来，所以勤动口是掌握国际音标发音的关键。俗话说，"三天不写手生，三天不念口生"，说的就是要加强动手动口能力的培养。因此学习国际音标，要时时加强语音训练，勤动口，反复实践练习，在实践中比较，在实践中体会差别，做到熟能生巧，这样自然就掌握国际音标的发音了。
重点音标讲解
单元音
[i:] =“一”
[ɪ]：[ɪ]开口要比[i:]稍大，注意比较两图口型。
[e] 嘴张45°，[æ]嘴张90°
[ɜ:r] [ər]=“二”
[ə]=额（不卷舌）
[ʌ]：开口比“啊”略小
[ɑ:r]=卷舌的“啊”
[ɑ] =“啊”
[ɔ] =开口稍大的“哦”
[ɔ:r]=卷舌的“哦”
[u:]核心：双唇由半开微突，过渡到合嘴圆唇
[ʊ] 发成噘嘴的[ə],气流向外。
双元音
双元音较简单，大多数可进行类比，注意双元音的重音在第一个音标，即前一个音读的稍重，后一个音读的较轻。
[eɪ]=“A”
[aɪ]=“I”
[əʊ]=“O”
[ɔɪ]=“哦一”
[ɪə]=ear
[eə]=air
[ʊə]=“乌尔”
辅音
大部分辅音跟“汉语拼音”都有相似之处，直接看视频模仿即可，这里只讲解易错发音。
爆破音：
[t] [p] [k] 不要读成[tə] [pə] [kə] 注意：它们声带不震动
摩擦音：
[f][v] 咬唇音，注意上齿咬下唇
[θ][ð]
上下齿轻咬舌头，发音时能看到你的舌头露出
[ʃ]=不发音的“诗” [ʒ]= “日”
[r]=撅嘴＋卷舌的“热” [h]=不发音＋舌头平放的“喝”
鼻音
[m] 合嘴
[n] 舌前部抵住上颚
[ŋ] 嘴巴张开
舌侧音[l]
元音前：跟拼音“l”发音一致元音后：发“l”的前半段
半元音
[j] “也”
[w] =圆唇噘嘴的“我”
破擦音
[tʃ]= 不发声的“吃”
[dʒ]= “居”
[ts]=不发声的“次”
[dz]=“子”
[tr] 先发“t”，在发“r”，最后结合在一起
[dr] 同上
词汇拼读
1、规划拼读任务，拿出单词书或课本词汇表，找只含1~2个音节的单词拼读，20个为一组，每天练习3组，当然如果有时间，多进行几组也OK，加强效果。后期难度逐渐加大。
2、输入法识别词汇，每拼读一个词汇，都对着X飞输入法的语音识别功能朗读，看能否被输入法识别出单词，用机器来检测是否读的准确。
3、听词汇跟读，不管输入法识别出单词，还是没识别出单词，都要查手机字典，来听一遍听力，并跟读，模仿语调和轻重读音。
例如：Cash driver apartment money breakfast lawyer agency
学习计划
1、国际音标，一共48个，每天学4个，12天学完，元音和辅音每天各学习两个。
2、学完以后结合和音标相关的单词，每天坚持读一个小时，第二天要把第一天的一块儿读，第三天要把前两天的一块儿读，依次类推，坚持学完所有的音标，就可以读字典上任何一个单词。
3、长期坚持下去，会发现其实很多字母和音标有着关联，比如ph都发音标f的音，字母u发尖a的音，类似的规律，当大家坚持下来以后会发现很多，同时你甚至可以听到单词的发音就能把单词拼出来，直接就把背单词的问题解决了，音标会读，单词会读，单词会背，听力当然也不再是问题。自己总结出来的规律说明真的学会了，同时自己得出来的结论要比老师直接告诉你印象更深刻，同时最重要的是用起来更容易。
注意事项
1、了解发音要领，模仿老师口型
学习语音，一定要注意口型，并仔细揣摩每个音标的发音要领，特别是相似音标的发音区别。
零基础学员不要以为盯着老师的口型就好了，其实发音很多都是内部器官看不到的， 所以需要老师正确的发音示范，跟着老师一起读，然后再加上老师给的一些技巧，继续跟读，老师感觉哪有问题，再帮着纠正，这样一系列过程才是练成标准发音的秘籍。
2、 单词拼读实战，一对一纠正错误
养成一口纯正口语最重要的还是练习练习再练习，单词拼读实战训练，巩固你的发音。不断读，不断纠正，训练单个音标到训练多个单词，在学习语音的过程中，再掌握一些基础的词汇。
3、辩音练习，纠正错误，掌握发音规律
训练难度会随着课程的深入不断加强，但还是训练相同的内容，一节课很多类似的训练内容。音标中很多类似的发音，将相似音放在一起对比再练习，舌头和耳朵在这很重要。
%3Chowto_content%3E[{"type":"paragraph","attrs":{"is_abstract":true},"children":[{"type":"text","text":"音标是学习英语的第一步，想要学好音标需要认识音标、会读音标，这样以后才能认识单词。在学习音标前，我们要先知道国际音标有48个，元音有20个，辅音有28个，元音又分为单元音和双元音，单元音有12个，双元音有8个。","id":""}],"text":"","id":"X0ayd2WScoy4M6xsFVmcneA8n8f"},{"type":"heading","attrs":{"level":1},"children":[{"type":"text","text":"音标数目","id":""}],"text":"","id":"XGMMdqqKGoIkyGxmsOVcclDvnFd"},{"type":"paragraph","children":[{"type":"text","text":"在上表中，我们可以看到音标有48个，现在我们常说的国际音标也是48个。","id":""}],"text":"","id":"AESAdWCuQoQUiuxmQkVcGNVXnbe"},{"type":"paragraph","children":[{"type":"text","text":"可以点击下面链接学习音标。","id":""}],"text":"","id":"E20kdWCCso4ykCx45GjcqgWynqa"},{"type":"paragraph","children":[{"type":"text","text":"《【48个英语音标示范读音-哔哩哔哩】 ","id":""},{"type":"external_link","attrs":{"url":"https://b23.tv/mt9vVaK"},"children":[{"type":"text","text":"https://b23.tv/mt9vVaK","id":""}],"text":"","id":""},{"type":"text","text":"》","id":""}],"text":"","id":"AqckdkO2SoWKyoxQJlCcXjKcn4f"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"元音部分","id":""}],"text":"","id":"MsOsda4UyoA0yUx4xP6czKClnJg"},{"type":"image","attrs":{"height":345,"note":[{"type":"text","text":"元音部分","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/a663fdb6f1284e47acca44c09060b0a2","width":694},"text":"","id":"AEKudCk2So0cmMxCAIeceBvxnjf"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"辅音部分","id":""}],"text":"","id":"KisEdmSmgogIwoxC4ZMcG3QknLe"},{"type":"image","attrs":{"height":601,"note":[{"type":"text","text":"辅音部分","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/7467dcbf994549a5a6381df079b4301f","width":561},"text":"","id":"PAIEdU6suogWcexSCXRc664TnUf"},{"type":"heading","attrs":{"level":1},"children":[{"type":"text","text":"音标的分类","id":""}],"text":"","id":"YouadwUQwosyeyxasemc2PIHnjb"},{"type":"paragraph","children":[{"type":"text","text":"最实用的分类方式是：元音=长元音+短元音+双元音；辅音=清辅音+浊辅音。","id":""}],"text":"","id":"IwWMdM0y4okSc6xUXz8cZOKMnWg"},{"type":"paragraph","children":[{"type":"text","text":"英语一共有48个国际音标，包括20个元音，28个辅音。","id":""}],"text":"","id":"ZEYEdomcAoIWSIx0gs6ctJvEnHg"},{"type":"paragraph","children":[{"type":"text","text":"20个元音包括5个长元音：/i:/、/ɜ:/、/u:/、/a:/、/ɔ:/；","id":""}],"text":"","id":"TOEMdsCmEo8wmuxy9sgchI0Dncu"},{"type":"paragraph","children":[{"type":"text","text":"7个短元音：[i] [ə] [ɔ] [u] [ʌ] [e] [æ]；","id":""}],"text":"","id":"JSgsdwwsWoc2i8xcLMycBbyfnae"},{"type":"paragraph","children":[{"type":"text","text":"8个双元音：/eɪ、/aɪ/、/ɔɪ/、/ɪə/、/eə/、/ʊə/、/əʊ/、/aʊ/；","id":""}],"text":"","id":"FEqydSEaYoYgAExG0OJcpQCinVe"},{"type":"paragraph","children":[{"type":"text","text":"注意：","id":""}],"text":"","id":"QgMudGYi4ooOcUxmocWcCoCEn1I"},{"type":"paragraph","children":[{"type":"text","text":"1、长元音顾名思义就是发的音比较长而饱满；短元音则发的音比较短而急；","id":""}],"text":"","id":"CUm2dg0ayooas8xw7mKc1LHmnHb"},{"type":"paragraph","children":[{"type":"text","text":"2、双元音就是两个单元音拼在一起，成为组合音。双元音发音的特点是前面的单元音发音长，后面的发音比较短。","id":""}],"text":"","id":"L6kydWcCEosSoGx4YDdcStKNnRb"},{"type":"paragraph","children":[{"type":"text","text":"28个辅音包括：轻辅音/p/ /t/ /k/ /f/ /θ/ /s/ /ʃ/ /ts/ /tʃ/ /tr/ /h/","id":""}],"text":"","id":"AIKwdykA4ogsCMxghM8cwNI2ndd"},{"type":"paragraph","children":[{"type":"text","text":"浊辅音 /b/ /d/ /g/ /v/ /ð/ /z/ /ʒ/ /dz/ /dʒ/ /dr/ /r/","id":""}],"text":"","id":"EKwedeuCIoQOQOxsPGjcKnRinVe"},{"type":"paragraph","children":[{"type":"text","text":"鼻音 /m/ /n/ /ŋ/","id":""}],"text":"","id":"NsCOdg4ACo2C8cxYDOvc9jprnMe"},{"type":"paragraph","children":[{"type":"text","text":"半元音 /j/ /w/","id":""}],"text":"","id":"YgEed6IysogkMcxCm9rcZCI9nMc"},{"type":"paragraph","children":[{"type":"text","text":"边音 /ǀ/","id":""}],"text":"","id":"UkYUdw6iMoqSiqxwvFGcq3HTnTb"},{"type":"image","attrs":{"height":551,"note":[{"type":"text","text":"音标的分类","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/6872a8bb79f14f40989a6ed6bc41be7a","width":720},"text":"","id":"C4qGduOAkoiWuQx0ixicZGvqnPh"},{"type":"heading","attrs":{"level":1},"children":[{"type":"text","text":"发音技巧","id":""}],"text":"","id":"VYc4dsOwco02wAxAp27chauenkc"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"长元音","id":""}],"text":"","id":"MI8CdGMgmoi24ox6Isuc2rBwnSg"},{"type":"paragraph","children":[{"type":"text","text":"点击这个视频学习长元音发音。《【元音音标（长元音）-哔哩哔哩】 ","id":""},{"type":"external_link","attrs":{"url":"https://b23.tv/xz9mOz3"},"children":[{"type":"text","text":"https://b23.tv/xz9mOz3","id":""}],"text":"","id":""},{"type":"text","text":"》","id":""}],"text":"","id":"AmiUdgiYaoo2m8xCLThcfQzVnob"},{"type":"paragraph","children":[{"type":"text","text":"5个长元音/i:/、/ɜ:/、/u:/、/a:/、/ɔ:/发音技巧。","id":""}],"text":"","id":"FKwydmY08oE4Esxsthgc7bG6ngf"},{"type":"paragraph","children":[{"type":"text","text":"（1）/i:/发音技巧：","id":""}],"text":"","id":"JICedKKGioa2S6xOb2IcdXk7n31"},{"type":"paragraph","children":[{"type":"text","text":"发音时舌尖抵下齿，口形扁平。在发音的时候要尽量拉长，就像古人喝醉酒以后吟诗的感觉。","id":""}],"text":"","id":"PuU6dGQ4goEwuyx0SHAcyATXnRh"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：bee [biː] n. 蜜蜂；see [siː] v. 看见，参看","id":""}],"text":"","id":"HoymdmuGiocUiExgVgicDvQJn2b"},{"type":"image","attrs":{"height":306,"note":[{"type":"text","text":"长元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/11401e7cc5bc444dbe441c1675fed41f","width":451},"text":"","id":"Jwu8dI462oaeoYx2YiTciWTqnvE"},{"type":"paragraph","children":[{"type":"text","text":"（2）/ɜ:/发音技巧：","id":""}],"text":"","id":"Ts2qdA6SgoseSMxKkuqcBll6nug"},{"type":"paragraph","children":[{"type":"text","text":"/ɜ:/是长元音，近似于北京腔的“儿”话音，如“花儿”的“儿”。发好这个音，关键在于卷舌！","id":""}],"text":"","id":"OYYudyQECoAUWCxAXCXcpSQNnwb"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：shirt [ʃə:t] n. 衬衫,男士衬衫；nurse [nə:s] n. 护士,保姆","id":""}],"text":"","id":"COSGdekU0o4gUuxMXnMcC6pCn2c"},{"type":"image","attrs":{"height":377,"note":[{"type":"text","text":"长元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/623ec09f755c4250bf94380ee9544915","width":562},"text":"","id":"FCiYdGaciomUW2xG0SicnSgFnLd"},{"type":"paragraph","children":[{"type":"text","text":"（3）/u:/发音技巧","id":""}],"text":"","id":"PWOIdEuS2o0WmaxWew6cVNb0nEf"},{"type":"paragraph","children":[{"type":"text","text":"发这个音时双唇用力向前突出，有点像拉长了音说“乌”，但要注意，“乌”的口形较扁。","id":""}],"text":"","id":"KGkEdI2kMos20Ox2r4qcCFyXnnc"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：moon [mu:n] n. 月球,月亮；room [ruːm] n. 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远的","id":""}],"text":"","id":"YAQsdCAoGosGOqxQt5octrTLnYc"},{"type":"image","attrs":{"height":273,"note":[{"type":"text","text":"长元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/025ef979d9624dbc88706798e493e87b","width":454},"text":"","id":"JsAodyMG4oaAWUx0eNaclgPRnU7"},{"type":"paragraph","children":[{"type":"text","text":"（5）/ɔ:/发音技巧","id":""}],"text":"","id":"VyMWdKGuYouWEGxCWxVch2RmnXg"},{"type":"paragraph","children":[{"type":"text","text":"发这个音时，双唇稍稍收圆，并向前突出，发音接近于汉语“嗷”。这是个长元音，记住：长元音一定要拉长，发出来才好听。","id":""}],"text":"","id":"MgM2dcYGCo46QcxQbwMc94Nynih"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：door [dɔ:r] n. 门； short [ʃɔ:t] adj. 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/ɔ/、/u/、/ʌ/、/e/、/æ/","id":""}],"text":"","id":"JQe8de0WgoW4WIxIf6EcSf5Jn8g"},{"type":"paragraph","children":[{"type":"text","text":"（1）/i/发音技巧","id":""}],"text":"","id":"OeiSdAac6oeg4QxICt4cMrZ1ngb"},{"type":"paragraph","children":[{"type":"text","text":"它是个短元音，发音要短促而轻快。","id":""}],"text":"","id":"KyOcdmKcYo2yg0xc9CLchnc0nFg"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：big [bɪɡ] adj. 大的,庞大的；Fit [fit] v. 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面，边","id":""}],"text":"","id":"HIYQdm4KkocmioxVAXPcjTFInvy"},{"type":"image","attrs":{"height":303,"note":[{"type":"text","text":"双元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/1fac52f81d3e43b4ad93559d84c6e4fd","width":452},"text":"","id":"GW2id2oWuoywqex6iJZcG5KXnWh"},{"type":"paragraph","children":[{"type":"text","text":"（3）/ɔɪ/发音技巧","id":""}],"text":"","id":"AOWIdIc8moigIixsbHIckhi8n5G"},{"type":"paragraph","children":[{"type":"text","text":"发音时双唇从圆到扁，口形从开到合。接近于汉语发音“奥一”","id":""},{"type":"text","marks":[{"type":"strong"}],"text":"。","id":""}],"text":"","id":"FSw4ducquoQKMuxMtIScMy4wnWd"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：oil [ɔil] n. 油，石油；noise [nɔɪz] n. 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单纯的","id":""}],"text":"","id":"IqQidGY8uou04vxQr5ucq8izn2T"},{"type":"image","attrs":{"height":338,"note":[{"type":"text","text":"双元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/c63377faff584578850c4f931e0964a4","width":500},"text":"","id":"G2Uod4AO2oA0yuxOgbYcsRAUnbg"},{"type":"paragraph","children":[{"type":"text","text":"（7）/əʊ/发音技巧","id":""}],"text":"","id":"AKMadGucOoaaGIxQFbicoXY5n6b"},{"type":"paragraph","children":[{"type":"text","text":"舌位由半低到高，口形由半开到小。接近于汉语发音“呃屋”。","id":""}],"text":"","id":"KkSUdWMwwo4CE8xKwmhcnBqwnyc"},{"type":"paragraph","children":[{"type":"text","text":"单词举例： flow [fləu] ：vi. 流；glow [ɡləʊ] ：vi. 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/h/","id":""}],"text":"","id":"JY04deUyUo4SOIx00V9cNrjgn2e"},{"type":"paragraph","children":[{"type":"text","text":"11个浊辅音 /b/ /d/ /g/ /v/ /ð/ /z/ /ʒ/ /dz/ /dʒ/ /dr/ /r/","id":""}],"text":"","id":"Aya6dI06WoYGm0xgFG8cd2RWnVd"},{"type":"paragraph","children":[{"type":"text","text":"注意：","id":""}],"text":"","id":"DCAKdYKa6o6CskxSKjOcMmqYnxe"},{"type":"paragraph","children":[{"type":"text","text":"清辅音：发音时送气，声带不颤动（颤不颤用手放在喉咙上就知道了）","id":""}],"text":"","id":"V4c8d0oaKoiiasxSJbIc3Phpn8z"},{"type":"paragraph","children":[{"type":"text","text":"浊辅音：发音时不送气(拿张纸放在嘴前，纸没有被吹开)，声带颤动。","id":""}],"text":"","id":"C6msd8Wsao4MCox3aGXchxhTnit"},{"type":"paragraph","children":[{"type":"text","text":"（1）/p/ /b/谐音分别为“普”、“卜”，都省去韵母成分","id":""}],"text":"","id":"WqgqdeYCwoquUGxIpR6cp8i9n6b"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：/p/是清辅音，声带不振动；/b/是浊辅音，声带振动。","id":""}],"text":"","id":"Q2iUduAywo0QcsxAPIvcauRYn1e"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/p/：pen [pen] n.钢笔；pin [pin] n.大头针","id":""}],"text":"","id":"I6YGdymweowsukxi0Chcjet4nbe"},{"type":"paragraph","children":[{"type":"text","text":"/b/：bike [baik] n.自行车；beg [beg] v.乞求","id":""}],"text":"","id":"IukEd2acUomqsix61ZlcYRZgntc"},{"type":"imageList","children":[{"type":"image","attrs":{"height":291,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/606b063e5abc4abda1a64a5bcd15ed33","width":453},"text":"","id":"GAAodsy42oGcEOxqesecgGainDg"},{"type":"image","attrs":{"height":279,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/62b2c2ff83cd446e913fc3894b60f5ed","width":453},"text":"","id":"LocqdA2WqoWwOmx4iqoc1Co1nzd"}],"text":"","id":"OUu0dw0IUoCAoKxWuwQcERpSn2g"},{"type":"paragraph","children":[{"type":"text","text":"（2）/t/ /d/分别谐音“特”、“得”。","id":""}],"text":"","id":"OUu0dw0IUoCAoKxWuwQcERpSn2g"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：/t/是清辅音，声带不振动；/d/是浊辅音，声带振动。","id":""}],"text":"","id":"WqgudmymyoWeMyxG4qAcXd5Nn3f"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/t/ ：ten [ten] num； test [test] n. 试验, 考验","id":""}],"text":"","id":"CmCsdscSUougQExs3LHcC6Yvnxc"},{"type":"paragraph","children":[{"type":"text","text":"/d/： student [ˈstudnt] n.学生； date [deɪt] n.日期、日子、约见时间 v.注明日期、写上日期","id":""}],"text":"","id":"QEwYdeUuqoceaWxmGpgcCQRAnaf"},{"type":"imageList","children":[{"type":"image","attrs":{"height":285,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/a42294e34f854b1db31a0c38ef37302c","width":450},"text":"","id":"Q8KYdagoIo4k20x8FBYcKkY5ng9"},{"type":"image","attrs":{"height":303,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/904cd5e38687477288a3126fcc4f1018","width":454},"text":"","id":"EOGSdg44io6MwMxwFg2cxsvAnPf"}],"text":"","id":"DQQedqwyMooIEkxIKJIcVruHnlb"},{"type":"paragraph","children":[{"type":"text","text":"（3）/k/ /g/分别谐音“可”、“嗝”。","id":""}],"text":"","id":"DQQedqwyMooIEkxIKJIcVruHnlb"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：发音时舌后部隆起紧贴软颚，憋住气，然后突然分开，气流送出口腔，形成爆破音。/k/是清辅音，声带不要振动；/g/是浊辅音，声带需要振动。","id":""}],"text":"","id":"CiO0dy8SCoiem2xKge6ccUbyn7e"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/k/ ：kite [kait] n. 风筝；cake [keɪk] n. 蛋糕","id":""}],"text":"","id":"FUQodyeyyoWuQAx2JGYcZNT1nqd"},{"type":"paragraph","children":[{"type":"text","text":"/g/： glove [ɡlʌv] n. 手套；girl [ɡə:l] n. 女孩","id":""}],"text":"","id":"AQIOdQAAIoSki6xy8ITcIpXtnmh"},{"type":"imageList","children":[{"type":"image","attrs":{"height":305,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/14d7ac9a6f4f404893f06bdabb1aa226","width":490},"text":"","id":"Emi6dSeEKo2WoixmcDrcz6VHnU6"},{"type":"image","attrs":{"height":304,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/06964c4beb5c4fce98d2def6ba8ebbca","width":493},"text":"","id":"DYMkdcSk4oSS0AxYncocwbmfnZc"}],"text":"","id":"DySedIAYgoKsywxoVI4cNSDinKe"},{"type":"paragraph","children":[{"type":"text","text":"（4）/f/ /v/","id":""}],"text":"","id":"DySedIAYgoKsywxoVI4cNSDinKe"},{"type":"paragraph","children":[{"type":"text","text":"/f/谐音“府”，/v/就是北方人把W读成V那种感觉。","id":""}],"text":"","id":"ISoKdAUgYoGIyExI5y6cPFHfnPh"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：发音前，上齿咬住下嘴唇，然后使气流由唇齿间的缝隙中通过，从而引起摩擦。","id":""}],"text":"","id":"RM62de2eqoAkcixAxO3c7o2nn2b"},{"type":"paragraph","children":[{"type":"text","text":"/f/是清辅音，发音时声带不震动；/v/是浊辅音，发音时声带振动。","id":""}],"text":"","id":"AGkSdk02UoUYoqx87ogcwnwpnPf"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/f/：flower ['flaʊər] n. 花；fly [flai] vi.飞, 飞行","id":""}],"text":"","id":"DmI8dMaAyocKYixCAJOcvEDznmb"},{"type":"paragraph","children":[{"type":"text","text":"/v/：love [lʌv] v. 爱；seven [ˈsevən] num. 七","id":""}],"text":"","id":"CaQOdgSIQogyCOxO4sGcBbGqnkg"},{"type":"imageList","children":[{"type":"image","attrs":{"height":307,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/8ce3c52756514e448ddc1d518e55ecdf","width":450},"text":"","id":"Pam6duQkAoyQ6Oxq6dwcgin7nTe"},{"type":"image","attrs":{"height":307,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/0d517eafc9904db59404a654d6aabfd9","width":499},"text":"","id":"A6ugd446kocAo6xgNYQcDw1hnId"}],"text":"","id":"XICgdYG6eowkcoxiK6zcQDIVn3f"},{"type":"paragraph","children":[{"type":"text","text":"(5)/θ/ /ð/ 牙齿轻咬舌尖发出的音","id":""}],"text":"","id":"XICgdYG6eowkcoxiK6zcQDIVn3f"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：发音时，舌尖微微伸出，置于上下门齿之间，舌尖和下齿之间的气流通道非常窄小，气流从舌齿间的窄缝中通过。/θ/是清辅音，发音时声带不振动；/ð/是浊辅音，发音时声带振动。","id":""}],"text":"","id":"XmG0de0CookKwKxgJVJctctcnbc"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/θ/：three [θri:] num. 三； throw [θrəʊ] vi. 投掷","id":""}],"text":"","id":"BQUadqEywoMcs2xEtzIc5zkmnfb"},{"type":"paragraph","children":[{"type":"text","text":"/ð/：this [ðɪs] pron. 这,这个，这里； mother [ˈmʌðə(r)] n. 母亲","id":""}],"text":"","id":"NGMedc0I2oEIOEx6qDWc6Ca4nwg"},{"type":"imageList","children":[{"type":"image","attrs":{"height":430,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/50168da9a42b477395fa447a59aadf00","width":640},"text":"","id":"TS0MdAOiIoWak2x4Fr2cXJLRneg"},{"type":"image","attrs":{"height":250,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/fe852c5bda9443b4b98bcb1ed73950ab","width":456},"text":"","id":"Y6o6dYI68oOO4ixYzmUcUdwlnHg"}],"text":"","id":"MCEgdOoEkoUE2qxAtnfcviE7nSg"},{"type":"paragraph","children":[{"type":"text","text":"(6)/s/ 谐音“丝”，/z/“zi”","id":""}],"text":"","id":"MCEgdOoEkoUE2qxAtnfcviE7nSg"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：发音时舌端靠近齿龈，气流由舌端齿龈间送出。/s/是清辅音，声带不振动；/z/是浊浦音，声带振动。","id":""}],"text":"","id":"MiYMdEsIcom0uoxgfRFcbXodnAg"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/s/：school [sku:l] n. 学校，学院；bus [bʌs] n. 公共汽车","id":""}],"text":"","id":"WO6kd6cMWoAM02xGkWKc7Bunnnc"},{"type":"paragraph","children":[{"type":"text","text":"/z/：please [pli:z] int.请；zoo [zu:] n.动物园","id":""}],"text":"","id":"IgmKdaGiooyg8ExgVM2cEGJAnoh"},{"type":"imageList","children":[{"type":"image","attrs":{"height":271,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/9a735a6fd556430899e72f213603429c","width":453},"text":"","id":"IYIEdaM6co0Mo6xsd9CcEcfGnrf"},{"type":"image","attrs":{"height":217,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/cbd3bbe2132a47e09a970ca158685fd7","width":454},"text":"","id":"S6C8duMs0omqiKxkfZncVmJSnIb"}],"text":"","id":"RKu4dWEeIo4Og6xqiP7cXVdwnKb"},{"type":"paragraph","children":[{"type":"text","text":"(7)/ts/ /dz/分别谐音“次”、“自”","id":""}],"text":"","id":"RKu4dWEeIo4Og6xqiP7cXVdwnKb"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：舌端先贴住上齿龈，堵住气流，气流送出口腔。/ts/是清辅音，声带不振动，/dz/是浊辅音，声带振动。","id":""}],"text":"","id":"Wu2AdkuSioKeekxGWiWcUNN1nFf"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/ts/：cats [kæts] n. 猫( cat的名词复数 )；hats [hæts] n. 帽子( hat的名词复数 ) ","id":""}],"text":"","id":"DOksdQsWUoKGA2xETz0chmFantf"},{"type":"paragraph","children":[{"type":"text","text":"/dz/：hands [hændz] n.手；lands [lændz] n.陆地","id":""}],"text":"","id":"CMmSdKgc0oK828xcVxeci6yGnOg"},{"type":"imageList","children":[{"type":"image","attrs":{"height":289,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/8fdc13488fbc4d59a98f9f0713aefe7c","width":450},"text":"","id":"P8KydWaQYo8qWUxQppkc4qdhngb"},{"type":"image","attrs":{"height":276,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/7c7a93711b0e46cc83a527c60d527179","width":451},"text":"","id":"PkmQd6QMeoIcCIxoQSfcvdqVnmb"}],"text":"","id":"Ng8qda44kouo0UxWAN2cpPcpnkb"},{"type":"paragraph","children":[{"type":"text","text":"(8)/tr/ /dr/分别谐音“戳”、“捉”","id":""}],"text":"","id":"Ng8qda44kouo0UxWAN2cpPcpnkb"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：舌尖贴齿龈后部，气流冲破阻碍发出短促的/t/后立即发/r/。/tr/是清辅音，声带不振动；/dr/是浊辅音，声带振动。","id":""}],"text":"","id":"GSKsdMQi0o82OexWotqcSV0KnVc"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/tr/ : tree [tri:] n. 树，木料；try [traɪ] vt.\u0026 vi. 试图 ","id":""}],"text":"","id":"GGkKdsqAqo0C8WxqIJucE48Anzb"},{"type":"paragraph","children":[{"type":"text","text":"/dr/：dress [dres] n.连衣裙；drink [drɪŋk] v.喝酒","id":""}],"text":"","id":"HcYWdO6moomiWCxi6X3c322tnUe"},{"type":"imageList","children":[{"type":"image","attrs":{"height":306,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/8cd7b6ea3573404d915c2b39fdd668ad","width":454},"text":"","id":"Vg4UdMsoWosWm6xmPRjcCCNMnyQ"},{"type":"image","attrs":{"height":296,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/700de1de8f2b402893d73b6fd25b5342","width":452},"text":"","id":"OsM4dSIkIouswGxiw7LcHHrMnjb"}],"text":"","id":"JSaEd8UAsoau4axA33tcPSTUnLe"},{"type":"paragraph","children":[{"type":"text","text":"(9)/∫/ /ʒ/分别谐音“诗”、“日”","id":""}],"text":"","id":"JSaEd8UAsoau4axA33tcPSTUnLe"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：/∫/是清辅音，声带不振动；/ʒ/是浊辅音，声带振动。","id":""}],"text":"","id":"PKmAda0ceooIAExiq07crsVtnid"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/∫/：English [ˈɪŋglɪʃ] adj. 英格兰的； 英国的；rubbish [ˈrʌbɪʃ] n. 垃圾；","id":""}],"text":"","id":"FGIidicIkoCGCKxKo0PcQBYlnhd"},{"type":"paragraph","children":[{"type":"text","text":"/ʒ/：pleasure [ˈpleʒə] n.快乐，愉快；casual [ˈkæʒuəl] adj意外的，偶然的","id":""}],"text":"","id":"MwwIdAKiooqy2Cxak94c5PDbnGg"},{"type":"imageList","children":[{"type":"image","attrs":{"height":285,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/8f332b0d40c74d34ae86cb1fa3ca05e7","width":454},"text":"","id":"DwsYdMccsog0iYxISsfcHUVinNH"},{"type":"image","attrs":{"height":228,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/f540e592612a4386a861f7ad67e4073c","width":453},"text":"","id":"ISiYdkQoGoGQe0xKa7JcQsU3n3d"}],"text":"","id":"SMc2d28g4oE0muxS4CIcteUNn3b"},{"type":"paragraph","children":[{"type":"text","text":"（10）/t∫/ /dʒ/分别谐音“吃”、“之”","id":""}],"text":"","id":"SMc2d28g4oE0muxS4CIcteUNn3b"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：发音时舌身抬高，舌端抵上齿龈后部，气流通过时发出破擦音。/t∫/是清辅音，声带不振动；/dʒ/是浊辅音，声带振动。","id":""}],"text":"","id":"U0gWdO4iMoCAaoxYfM3cC5m6n7b"},{"type":"paragraph","children":[{"type":"text","text":"单词举例：/t∫/： chalk [tʃɔ:k] n. 粉笔；chair [tʃeər] n. 椅子","id":""}],"text":"","id":"NK0ydWy0SoseSyxGoJMcJWW5nLd"},{"type":"paragraph","children":[{"type":"text","text":"/dʒ/：page [peɪdʒ] n.页 ；age [eɪdʒ] n.年龄","id":""}],"text":"","id":"OEesduWwUowgWuxm4gJcL9gGnuc"},{"type":"imageList","children":[{"type":"image","attrs":{"height":277,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/8b628a6b1e514fe0b391ed64c1367954","width":454},"text":"","id":"V86EdgUKGoouEOxqclNcNjX5nCh"},{"type":"image","attrs":{"height":267,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/6d921b622ffa4a38a273f436986ea872","width":445},"text":"","id":"VIo0dGc4yoCimMxU5WBcTgQNnSb"}],"text":"","id":"E0eYdWCA2oa2Q8xADQhcjsCsnVh"},{"type":"paragraph","children":[{"type":"text","text":"(11)/h/ /r/分别谐音“呵”、“若”，省去韵母成分。","id":""}],"text":"","id":"E0eYdWCA2oa2Q8xADQhcjsCsnVh"},{"type":"paragraph","children":[{"type":"text","text":"发音方法：","id":""}],"text":"","id":"M04md204koiKaQxcjQPccMzznXf"},{"type":"paragraph","children":[{"type":"text","text":"发/h/这个音时，嘴半开，气流从口腔不受阻碍而出，声带不振动，清辅音。","id":""}],"text":"","id":"K6Kidis8moccGAxjkUjcGKHMncS"},{"type":"paragraph","children":[{"type":"text","text":"发/r/这个音时，舌端上卷，靠近上齿龈附近，嘴唇张开并保持略圆状态，气流从口腔涌出，声带振动，属于浊辅音。","id":""}],"text":"","id":"Skk8dmsmoog2KwxWIvucX2Yvnyh"},{"type":"paragraph","children":[{"type":"text","text":"单词举例: /h/： hair [heə(r)] n.头发；hate [heɪt] v.恨，厌恶","id":""}],"text":"","id":"FeIKdecMEoOEEsxC2MDcxzKenug"},{"type":"paragraph","children":[{"type":"text","text":"/r/： sorry ['sɒrɪ] v.对不起 ；write [raɪt] v.写","id":""}],"text":"","id":"AmKEdA6O2oMuaCxQ3hLc0Vauneh"},{"type":"imageList","children":[{"type":"image","attrs":{"height":285,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/ae68233a2f1f4e0bae1ada1aafa601b2","width":455},"text":"","id":"B2IgdUQ0AoYG6wxYVJccq7VMnag"},{"type":"image","attrs":{"height":690,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/b5bc0da8fe7f4de1b056a6e261a0535d","width":1024},"text":"","id":"FoGadAwoIoQ8iux6WegcTMzCnlb"}],"text":"","id":"Tgm6dmyKQoWAASxyMtHcwHwxnwf"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"鼻音","id":""}],"text":"","id":"Tgm6dmyKQoWAASxyMtHcwHwxnwf"},{"type":"paragraph","children":[{"type":"text","text":"点击这个视频学习鼻音发音。《【（21）鼻音 m n ŋ | 英语音标发音口型示范 | 美式发音-哔哩哔哩】 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哪一个","id":""}],"text":"","id":"N8yMd808YogkeYxS8Bzcw8AnnZe"},{"type":"image","attrs":{"height":299,"note":[{"type":"text","text":"半元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/752d066e3d624ac5a0a385ff5a02f131","width":453},"text":"","id":"A2EAdkoKaoKUE8xCUKAcaFHvnrh"},{"type":"heading","attrs":{"level":1},"children":[{"type":"text","text":"学习步骤","id":""}],"text":"","id":"KGmUduwi2o4WWcxW8UAcAtf6nsh"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"抄写","id":""}],"text":"","id":"CyQmdY0woowyiWxQtzSct7zAn95"},{"type":"paragraph","children":[{"type":"text","text":"抄写音标，并了解音标特点。","id":""}],"text":"","id":"OKeud2iiGoSqEAxWbELcjRpgnqb"},{"type":"paragraph","children":[{"type":"text","text":"对音标的基本认知","id":""}],"text":"","id":"RaimdAOiYoEG8SxSmf2ceFeonGc"},{"type":"paragraph","children":[{"type":"text","text":"1、区别长短音带“：”的音标发音相对较长不带“：”的音标发音相对较短。","id":""}],"text":"","id":"Z2ScdmyGqomYqaxyqkdcLdq3nhL"},{"type":"paragraph","children":[{"type":"text","text":"2、区别清辅音和浊辅音核心区别：清辅音声带不震动，浊辅音声带振动。","id":""}],"text":"","id":"NYY8dyIYwo8OyAxcjYfcWTgKn3f"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"模仿练习","id":""}],"text":"","id":"V8YAdU2MgoEgOGxKAYHckkUAn0e"},{"type":"paragraph","children":[{"type":"text","text":"找合适的视频学习学习跟读。例如b站上《【赖世雄48个英语音标朗读示范，美音英音对照版-哔哩哔哩】 【","id":""},{"type":"external_link","attrs":{"url":"https://b23.tv/sHYQFZ3"},"children":[{"type":"text","text":"https://b23.tv/sHYQFZ3","id":""}],"text":"","id":""},{"type":"text","text":"】》、《【李咏梅老师英语（音标部分）——最牛的初中英语老师！没有之一！李咏梅国际音标 （完整版发音篇）-哔哩哔哩】 ","id":""},{"type":"external_link","attrs":{"url":"https://b23.tv/U1pmjNE"},"children":[{"type":"text","text":"https://b23.tv/U1pmjNE","id":""}],"text":"","id":""},{"type":"text","text":"》、《【纯正英式发音】这是BBC出品的到现在为止最棒的英语发音教程（完整版）-哔哩哔哩】 ","id":""},{"type":"external_link","attrs":{"url":"https://b23.tv/gZzDKl5"},"children":[{"type":"text","text":"https://b23.tv/gZzDKl5","id":""}],"text":"","id":""},{"type":"text","text":"》，以上几个视频都非常不错，详细讲解每个音标的读法。","id":""},{"type":"text","text":"注意视频一定至少跟读5遍，才能确保你的学习效果。","id":""}],"text":"","id":"KS4ydK4S6oiIQmxu0vncRSQHnMd"},{"type":"paragraph","children":[{"type":"text","text":"也可以通过下面这个视频观察发音口型的变化。","id":""}],"text":"","id":"IuCAd8Eeao4kYCxCirecwybinKd"},{"type":"paragraph","children":[{"type":"text","text":"《【48个英语音标示范读音-哔哩哔哩】 ","id":""},{"type":"external_link","attrs":{"url":"https://b23.tv/mt9vVaK"},"children":[{"type":"text","text":"https://b23.tv/mt9vVaK","id":""}],"text":"","id":""},{"type":"text","text":"》","id":""}],"text":"","id":"CMmAd4gewoQWIUxKQ07cNUeEnPb"},{"type":"paragraph","children":[{"type":"text","text":"1、模仿练习，学习国际音标的发音，要注意观察老师的口型，观察发音部位的变化，主动模仿发音，初学可以对着镜子模仿练习，特别是元音发音的舌位高低，口腔开口度大小与音色关系十分密切，可以通过镜子观察口型上的区别，观察舌尖、舌面、舌叶的活动情况，比如u和o、i和e、e和ε等等，掌握准确口腔开口度，对于准确发音具有非常重要的意义。","id":""}],"text":"","id":"XcymdwOWCo6CIGxa2tecRpqyncd"},{"type":"paragraph","children":[{"type":"text","text":"2、听音训练:学习国际音标需要认识48个音标，通过反反复复的听力练习，达到强化记忆。听音训练，如果有条件，可以多听老师朗读音标，也可以使用录音带反复听音，本课件中的每个音素，都可以循环倾听，强化记忆。","id":""}],"text":"","id":"N242dAYGAoY4MIxCel4c7gT7nOd"},{"type":"paragraph","children":[{"type":"text","text":"3、多动口，动口是加强实践的关键和核心，听音也好，模仿也好，比较也好，最终要归结到自己发音这一目标上来，所以勤动口是掌握国际音标发音的关键。俗话说，\"三天不写手生，三天不念口生\"，说的就是要加强动手动口能力的培养。因此学习国际音标，要时时加强语音训练，勤动口，反复实践练习，在实践中比较，在实践中体会差别，做到熟能生巧，这样自然就掌握国际音标的发音了。","id":""}],"text":"","id":"C8AGdQweWo6Eq4xwZQpcAzqTnGg"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"重点音标讲解","id":""}],"text":"","id":"NYgkdUaewoSIquxc48NcmqD7nQy"},{"type":"heading","attrs":{"level":3},"children":[{"type":"text","text":"单元音","id":""}],"text":"","id":"YW4wdUskoocOAwxuatBcuFsWn1d"},{"type":"paragraph","children":[{"type":"text","text":"[i:] =“一”","id":""}],"text":"","id":"HgwEd26sEoK8kaxa0MKcjHMRnRc"},{"type":"paragraph","children":[{"type":"text","text":"[ɪ]：[ɪ]开口要比[i:]稍大，注意比较两图口型。","id":""}],"text":"","id":"MSyYdOwSUo0k2axkAtYc5sddnbB"},{"type":"image","attrs":{"height":150,"note":[{"type":"text","text":"单元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/424933217c51464b98439d52a906dc79","width":313},"text":"","id":"XAeYdY8kMoOcUmx8IcRck6D9n7b"},{"type":"paragraph","children":[{"type":"text","text":"[e] 嘴张45°，[æ]嘴张90°","id":""}],"text":"","id":"FeQGdy2Smou2O6xURCZcVp3Lnae"},{"type":"image","attrs":{"height":145,"note":[{"type":"text","text":"单元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/6672fd2298724d35a280bead538ac3ae","width":306},"text":"","id":"RmM4dISSQoAMIcxygd5cxr6HnOe"},{"type":"paragraph","children":[{"type":"text","text":"[ɜ:r] [ər]=“二”","id":""}],"text":"","id":"TSo6dKsSWo2GYcxZjETc9G1GnDG"},{"type":"paragraph","children":[{"type":"text","text":"[ə]=额（不卷舌）","id":""}],"text":"","id":"HMsmdKmyKoAssoxAzOdc7OWnntg"},{"type":"image","attrs":{"height":169,"note":[{"type":"text","text":"单元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/23669fa681c94516b68dbd7dfbeacb30","width":287},"text":"","id":"Fo6QduWAwokykix49KRcfCJmnof"},{"type":"paragraph","children":[{"type":"text","text":"[ʌ]：开口比“啊”略小","id":""}],"text":"","id":"BGsmdsW6woUimYxOwpucaftfnNc"},{"type":"paragraph","children":[{"type":"text","text":"[ɑ:r]=卷舌的“啊”","id":""}],"text":"","id":"T4q6dQqcMo8UY4x6uROcurTungg"},{"type":"paragraph","children":[{"type":"text","text":"","id":""}],"text":"","id":"Yc4mdmGSQow40gxqCAGcOvvinBd"},{"type":"image","attrs":{"height":158,"note":[{"type":"text","text":"单元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/4a325dcff9bf444c93f02a661b7eb1dc","width":288},"text":"","id":"YI2udUmcEoUO2axUffDc55c0n5b"},{"type":"paragraph","children":[{"type":"text","text":"[ɑ] =“啊”","id":""}],"text":"","id":"GOUkd82oyoSQK2xGU3Yc38ITngg"},{"type":"paragraph","children":[{"type":"text","text":"[ɔ] =开口稍大的“哦”","id":""}],"text":"","id":"BY4wdeQqqoy6C6xqo3wc8LQdnVh"},{"type":"paragraph","children":[{"type":"text","text":"[ɔ:r]=卷舌的“哦”","id":""}],"text":"","id":"VieGd4caOoI2eIxKk63cHfKcnEh"},{"type":"imageList","children":[{"type":"image","attrs":{"height":110,"note":[{"type":"text","text":"单元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/47f4542a00f04f7aae6be6656657cf8c","width":114},"text":"","id":"IE8cdeAC4oMySuxgcAocFfSanZ3"},{"type":"image","attrs":{"height":110,"note":[{"type":"text","text":"单元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/710b04be027845d7be2106e9bbeb33a3","width":104},"text":"","id":"XmK2diS0YoCssGx8z5CcCyTSnad"},{"type":"image","attrs":{"height":110,"note":[{"type":"text","text":"单元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/710b04be027845d7be2106e9bbeb33a3","width":104},"text":"","id":"XmK2diS0YoCssGx8z5CcCyTSnad"},{"type":"image","attrs":{"height":110,"note":[{"type":"text","text":"单元音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/89ec169b38a04ab99190b396206e9400","width":98},"text":"","id":"UyMSdui2WoASQExMfVZcTvLqnrd"}],"text":"","id":"T8sYd4Wu8oaAOIxMxS7cIc9snLb"},{"type":"paragraph","children":[{"type":"text","text":"[u:]核心：双唇由半开微突，过渡到合嘴圆唇","id":""}],"text":"","id":"T8sYd4Wu8oaAOIxMxS7cIc9snLb"},{"type":"paragraph","children":[{"type":"text","text":"[ʊ] 发成噘嘴的[ə],气流向外。","id":""}],"text":"","id":"C4EUdoaeCoGgg2xA94WcKc7XnVg"},{"type":"heading","attrs":{"level":3},"children":[{"type":"text","text":"双元音","id":""}],"text":"","id":"RGS8duyAEoSGqgxas3DcrumNnog"},{"type":"paragraph","children":[{"type":"text","text":"双元音较简单，大多数可进行类比，注意双元音的重音在第一个音标，即前一个音读的稍重，后一个音读的较轻。","id":""}],"text":"","id":"Ww4IdocgUoaaeAxYJjwcra66neh"},{"type":"paragraph","children":[{"type":"text","text":"[eɪ]=“A”","id":""}],"text":"","id":"TciidSSSmoKY6MxOmfycHajin1A"},{"type":"paragraph","children":[{"type":"text","text":"[aɪ]=“I”","id":""}],"text":"","id":"QyWEdEi4eo0WC4xYBXWcKXKJn3g"},{"type":"paragraph","children":[{"type":"text","text":"[əʊ]=“O”","id":""}],"text":"","id":"OaqodkkAWoIIwixUvLJciK9Dnbg"},{"type":"paragraph","children":[{"type":"text","text":"[ɔɪ]=“哦一”","id":""}],"text":"","id":"EIkGdeWMMoCgCKxujKucWEgXnl7"},{"type":"paragraph","children":[{"type":"text","text":"[ɪə]=ear","id":""}],"text":"","id":"E6Wedoq6Go4KQKx0OLvcGKWAnNe"},{"type":"paragraph","children":[{"type":"text","text":"[eə]=air","id":""}],"text":"","id":"WKsUdcKGSouW0exAVi9cPsZcnWb"},{"type":"paragraph","children":[{"type":"text","text":"[ʊə]=“乌尔”","id":""}],"text":"","id":"JMWSdYuUAo84WexU5RncsFdWnYe"},{"type":"heading","attrs":{"level":3},"children":[{"type":"text","text":"辅音","id":""}],"text":"","id":"I6SAdQWcYoe2WexqIZ7cCguWnbd"},{"type":"paragraph","children":[{"type":"text","text":"大部分辅音跟“汉语拼音”都有相似之处，直接看视频模仿即可，这里只讲解易错发音。","id":""}],"text":"","id":"WOS4dUWgKoegoQxoBW1c0scNnCh"},{"type":"paragraph","children":[{"type":"text","text":"爆破音：","id":""}],"text":"","id":"AGwkdoY06oeKEExaYJdcMIPWnyc"},{"type":"paragraph","children":[{"type":"text","text":"[t] [p] [k] 不要读成[tə] [pə] [kə] 注意：它们声带不震动","id":""}],"text":"","id":"LqIEdUkemo8g6Gx2j13czIRNn4e"},{"type":"paragraph","children":[{"type":"text","text":"摩擦音：","id":""}],"text":"","id":"JAkqdWaUkoe4oQx6CBicKu6JnIf"},{"type":"paragraph","children":[{"type":"text","text":"[f][v] 咬唇音，注意上齿咬下唇","id":""}],"text":"","id":"UMwCdEUkWoQ6uQxwJcscTdTUnrd"},{"type":"image","attrs":{"height":146,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/2ad2d1355a204bcbae724b0dc07ceb1b","width":248},"text":"","id":"QugUdOeOOoC8yAxzSjzcPmdenp5"},{"type":"paragraph","children":[{"type":"text","text":"[θ][ð]","id":""}],"text":"","id":"BoGUd4UcUoS2eSxig5ac7Oh0nPf"},{"type":"paragraph","children":[{"type":"text","text":"上下齿轻咬舌头，发音时能看到你的舌头露出","id":""}],"text":"","id":"YesIdOoy4oEWmax6YWXcvXUSn1g"},{"type":"image","attrs":{"height":125,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/fb45b894066748d99889cbe3cbcf925d","width":239},"text":"","id":"XM0idmGoWosKc0xkOwdckSZZnUx"},{"type":"paragraph","children":[{"type":"text","text":"[ʃ]=不发音的“诗” [ʒ]= “日”","id":""}],"text":"","id":"BC0IdUyW4oiyGqxMzvxcAjzpnIg"},{"type":"image","attrs":{"height":144,"note":[{"type":"text","text":"辅音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/c8f6dc95aeda44ba960be5c6b0ae01ba","width":278},"text":"","id":"DSW8dw0eQoyYAIx87UScLiJbnvh"},{"type":"paragraph","children":[{"type":"text","text":"[r]=撅嘴＋卷舌的“热” [h]=不发音＋舌头平放的“喝”","id":""}],"text":"","id":"HMsYdguS0osqikxYJjncCMxjnie"},{"type":"heading","attrs":{"level":3},"children":[{"type":"text","text":"鼻音","id":""}],"text":"","id":"QYkOdgowEo6mSExYBRPc5wiznOc"},{"type":"paragraph","children":[{"type":"text","text":"[m] 合嘴","id":""}],"text":"","id":"LeSWdaaQkouGaMxKWxWcL08ense"},{"type":"paragraph","children":[{"type":"text","text":"[n] 舌前部抵住上颚","id":""}],"text":"","id":"XmKIdKGsiooa6ix6RbecaOExnUd"},{"type":"paragraph","children":[{"type":"text","text":"[ŋ] 嘴巴张开","id":""}],"text":"","id":"Xcusd4giYokcyGxKw8JccJM3nxd"},{"type":"imageList","children":[{"type":"image","attrs":{"height":114,"note":[{"type":"text","text":"鼻音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/6809d9fd4d604c999772a6441dca8739","width":157},"text":"","id":"HEw2dqIAYoysEoxiySQcHndjnud"},{"type":"image","attrs":{"height":114,"note":[{"type":"text","text":"鼻音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/6fa595b78ba94c89aadb1b2da94aaa69","width":157},"text":"","id":"CiAOdC6iooIYUEx0Yq6cvTGhnGd"},{"type":"image","attrs":{"height":114,"note":[{"type":"text","text":"鼻音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/6fa595b78ba94c89aadb1b2da94aaa69","width":157},"text":"","id":"CiAOdC6iooIYUEx0Yq6cvTGhnGd"},{"type":"image","attrs":{"height":114,"note":[{"type":"text","text":"鼻音","id":""}],"url":"{{image_domain}}tos-cn-i-qvj2lq49k0/5675b8cf0d67465db9106dd349b765ab","width":165},"text":"","id":"ICYydaeeyosCAQxq6mDcf2cJnvb"}],"text":"","id":"IM4QdgE82oU0wAxkvaac1cYYnPd"},{"type":"paragraph","children":[{"type":"text","text":"舌侧音[l]","id":""}],"text":"","id":"IM4QdgE82oU0wAxkvaac1cYYnPd"},{"type":"paragraph","children":[{"type":"text","text":"元音前：跟拼音“l”发音一致元音后：发“l”的前半段","id":""}],"text":"","id":"UAW4dyoO6ouEMwxU9DycGSVfnTd"},{"type":"paragraph","children":[{"type":"text","text":"半元音","id":""}],"text":"","id":"VYiUdiuoAoc0SkxJxQ7cKyODnHH"},{"type":"paragraph","children":[{"type":"text","text":"[j] “也”","id":""}],"text":"","id":"MiEYdKWOGoYoCsxaALDcfRxtn7d"},{"type":"paragraph","children":[{"type":"text","text":"[w] =圆唇噘嘴的“我”","id":""}],"text":"","id":"Eakqd8i8gomqCCx0C5ScvszAn3c"},{"type":"paragraph","children":[{"type":"text","text":"破擦音","id":""}],"text":"","id":"PWgEdOqSCo2cwaxgnVNcniofnCc"},{"type":"paragraph","children":[{"type":"text","text":"[tʃ]= 不发声的“吃”","id":""}],"text":"","id":"QUISdIOmYo8CAEx2xyfcxw1EnMg"},{"type":"paragraph","children":[{"type":"text","text":"[dʒ]= “居”","id":""}],"text":"","id":"XGoQdUkewoOKqwxg1NmcNvosncd"},{"type":"paragraph","children":[{"type":"text","text":"[ts]=不发声的“次”","id":""}],"text":"","id":"P8K6ducAkoeSccxsVFec10Icnve"},{"type":"paragraph","children":[{"type":"text","text":"[dz]=“子”","id":""}],"text":"","id":"V2CSdAm0ioYYcqxADoecjOXUn5T"},{"type":"paragraph","children":[{"type":"text","text":"[tr] 先发“t”，在发“r”，最后结合在一起","id":""}],"text":"","id":"PMwOdSKYsoO6yyxKW0vcyzhxnBb"},{"type":"paragraph","children":[{"type":"text","text":"[dr] 同上","id":""}],"text":"","id":"PqcCdaYuSosyuIx02oycX1iwnQh"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"词汇拼读","id":""}],"text":"","id":"I0GedsKk0oUgoOxuyXccgX1vnGe"},{"type":"paragraph","children":[{"type":"text","text":"1、规划拼读任务，拿出单词书或课本词汇表，找只含1~2个音节的单词拼读，20个为一组，每天练习3组，当然如果有时间，多进行几组也OK，加强效果。后期难度逐渐加大。","id":""}],"text":"","id":"YiK6dkyMqoE6KYxcZFecaO2Onic"},{"type":"paragraph","children":[{"type":"text","text":"2、输入法识别词汇，每拼读一个词汇，都对着X飞输入法的语音识别功能朗读，看能否被输入法识别出单词，用机器来检测是否读的准确。","id":""}],"text":"","id":"F82MdiS0OoEyEyxk1SicCu6vnaf"},{"type":"paragraph","children":[{"type":"text","text":"3、听词汇跟读，不管输入法识别出单词，还是没识别出单词，都要查手机字典，来听一遍听力，并跟读，模仿语调和轻重读音。","id":""}],"text":"","id":"GcOsd4I80oaSsExCYAecvtgonmg"},{"type":"paragraph","children":[{"type":"text","text":"例如：Cash driver apartment money breakfast lawyer agency ","id":""}],"text":"","id":"UAkYd6KyoosOe8xyaEycPumwn0d"},{"type":"heading","attrs":{"level":2},"children":[{"type":"text","text":"学习计划","id":""}],"text":"","id":"Ig8edugQyogYa8xmCTpcTKcgnRf"},{"type":"paragraph","children":[{"type":"text","text":"1、国际音标，一共48个，每天学4个，12天学完，元音和辅音每天各学习两个。","id":""}],"text":"","id":"Kk6IdUSM0omgecxaQbkcSsZsnve"},{"type":"paragraph","children":[{"type":"text","text":"2、学完以后结合和音标相关的单词，每天坚持读一个小时，第二天要把第一天的一块儿读，第三天要把前两天的一块儿读，依次类推，坚持学完所有的音标，就可以读字典上任何一个单词。","id":""}],"text":"","id":"QG6sdm2M4o68ouxYDuzcFDxhn9g"},{"type":"paragraph","children":[{"type":"text","text":"3、长期坚持下去，会发现其实很多字母和音标有着关联，比如ph都发音标f的音，字母u发尖a的音，类似的规律，当大家坚持下来以后会发现很多，同时你甚至可以听到单词的发音就能把单词拼出来，直接就把背单词的问题解决了，音标会读，单词会读，单词会背，听力当然也不再是问题。自己总结出来的规律说明真的学会了，同时自己得出来的结论要比老师直接告诉你印象更深刻，同时最重要的是用起来更容易。","id":""}],"text":"","id":"Km8odoYG4omMG2xQjwvctwuOn8e"},{"type":"heading","attrs":{"level":1},"children":[{"type":"text","text":"注意事项","id":""}],"text":"","id":"XS6WduK8gocSyQxwpyYc32mDnId"},{"type":"paragraph","children":[{"type":"text","text":"1、了解发音要领，模仿老师口型","id":""}],"text":"","id":"QaWwde6UQoWyyox8b3Yc0PnGngd"},{"type":"paragraph","children":[{"type":"text","text":"学习语音，一定要注意口型，并仔细揣摩每个音标的发音要领，特别是相似音标的发音区别。 ","id":""}],"text":"","id":"Jii2diISEoMkQixoveicLaPdn7b"},{"type":"paragraph","children":[{"type":"text","text":"零基础学员不要以为盯着老师的口型就好了，其实发音很多都是内部器官看不到的， 所以需要老师正确的发音示范，跟着老师一起读，然后再加上老师给的一些技巧，继续跟读，老师感觉哪有问题，再帮着纠正，这样一系列过程才是练成标准发音的秘籍。 ","id":""}],"text":"","id":"Pow0deEogocwqexqKJOchO9Qnbc"},{"type":"paragraph","children":[{"type":"text","text":"2、 单词拼读实战，一对一纠正错误","id":""}],"text":"","id":"KqAmdu0E4oWkkExaukOcf14rnHf"},{"type":"paragraph","children":[{"type":"text","text":"养成一口纯正口语最重要的还是练习练习再练习，单词拼读实战训练，巩固你的发音。不断读，不断纠正，训练单个音标到训练多个单词，在学习语音的过程中，再掌握一些基础的词汇。","id":""}],"text":"","id":"B0cyd2a4kowyACxM4E2cCki4nsi"},{"type":"paragraph","children":[{"type":"text","text":"3、辩音练习，纠正错误，掌握发音规律","id":""}],"text":"","id":"AQWQdmkKmoYcqyxsrTAcvvH8nhy"},{"type":"paragraph","children":[{"type":"text","text":"训练难度会随着课程的深入不断加强，但还是训练相同的内容，一节课很多类似的训练内容。音标中很多类似的发音，将相似音放在一起对比再练习，舌头和耳朵在这很重要。","id":""}],"text":"","id":"LyKYdA4oIoQC8exa2vjcYOc1nle"},{"type":"paragraph","children":[{"type":"text","text":"","id":""}],"text":"","id":"G4aGdqMEMoO2AGxkzAkcWRvAnHd"}]%3C%2Fhowto_content%3E光电传感器的符号？
光电传感器的电气符号: 电气符号大全，缺失：光电传感器的3590/9
1 继电器 K J
2 电流继电器 KA LJ
3 负序电流继电器 KAN FLJ
4 零序电流继电器 KAZ LLJ
5 电压继电器 KV YJ
6 正序电压继电器 KVP ZYJ
7 负序电压继电器 KVN FYJ
8 零序电压继电器 KVZ LYJ
9 继电器 KT SJ
10 功率继电器 KP GJ
11 差动继电器 KD CJ
12 信号继电器 KS XJ
13 信号冲击继电器 KAI XMJ
14 继电器 KC ZJ
15 热继电器 KR RJ
16 阻抗继电器 KI ZKJ
17 温度继电器 KTP WJ
18 瓦斯继电器 KG WSJ
19 合闸继电器 KCR或KON HJ
20 跳闸继电器 KTR TJ
21 合闸 继电器 KCP HWJ
22 跳闸 继电器 KTP TWJ
23 电源视继电器 KVS JJ
24 压力视继电器 KVP YJJ
25 电压 继电器 KVM YZJ
26 事故信号 继电器 KCA SXJ
27 继电保护跳闸出口继电器 KOU BCJ
28 手动合闸继电器 KCRM SHJ
29 手动跳闸继电器 KTPM STJ
30 加速继电器 KAC或KCL JSJ
31 复归继电器 KPE FJ
32 闭锁继电器 KLA或KCB BSJ
33 同期检查继电器 KSY TJJ
34 自动准同期装置 ASA ZZQ
35 自动重合闸装置 ARE ZCJ
36 自动励磁调节装置 AVR或AAVR ZTL
37 备用电源自动投入装置 AATS或RSAD BZT
38 按扭 SB AN
39 合闸按扭 SBC HA
40 跳闸按扭 SBT TA
41 复归按扭 SBre或SBR FA
42 试验按扭 SBte YA
43 紧急停机按扭 SBes JTA
44 起动按扭 SBst QA
45 自保持按扭 SBhs BA
46 停止按扭 SBss
47 控制开关 SAC KK
48 转换开关 SAH或SA ZK
49 测量转换开关 SAM CK
50 同期转换开关 SAS TK
51 自动同期转换开关 2SASC DTK
52 手动同期转换开关 1SASC STK
53 自同期转换开关 SSA2 ZTK
54 自动开关 QA
55 刀开关 QK或SN DK
56 熔断器 FU RD
57 快速熔断器 FUhs RDS
58 闭锁开关 SAL BK
59 信号灯 HL XD
60 光字牌 HL或HP GP
61 警铃 HAB或HA JL
62 合闸接触器 KMC HC
63 接触器 KM C
64 合闸线圈 Yon或LC HQ
65 跳闸线圈 Yoff或LT TQ
66 插座 XS
67 插头 XP
68 端子排 XT
69 测试端子 XE
70 连接片 XB LP
71 蓄电池 GB XDC
72 压力变送器 BP YB
73 温度变送器 BT WDB
74 电钟 PT
75 电流表 PA
76 电压表 PV
77 电度表 PJ
78 有功功率表 PPA
79 无功功率表 PPR
80 同期表 S
81 频率表 PF
82 电容器 C
83 灭磁电阻 RFS或Rfd Rmc
84 分流器 RW
85 热电阻 RT
86 电位器 RP
87 电感（电抗）线圈 L
88 电流互感器 TA CT或LH
89 电压互感器 TV PT或YH
10KV电压互感器 TV SYH
35KV电压互感器 TV UYH
110KV电压互感器 TV YYH
90 断路器 QF DL
91 隔离开关 QS G
92 电力变压器 TM B
93 同步发电机 GS TF
94 交流电动机 MA JD
95 直流电动机 MD ZD
96 电压互感器二次回路小母线
97 同期电压小母线（待并） WST或WVB TQMa,TQMb
98 同期电压小母线（运行） WOS`或WVBn TQM`a,TQM`b
99 准同期合闸小母线 1WSC,2WSC,3WSC
1WPO,2WPO,3WPO 1THM,2THM,3THM
100 控制电源小母线 +WC,-WC +KM,-KM
101 信号电源小母线 +WS,-WS +XM,-XM
102 合闸电源小母线 +WON,-WON +HM,-HM
103 事故信号小母线 WFA SYM
104 零序电压小母线 WVBz
中国的省会代码？
各省行政代码如下：北京市（110000 BJ）
天津市（120000 TJ）
河北省（130000 HB）
山西省（140000 SX）
内蒙古自治区（150000 NM）
辽宁省（210000 LN）
吉林省（220000 JL）
黑龙江省（230000 HL）
上海市（310000 SH）
江苏省（320000 JS）
浙江省（330000 ZJ）
安徽省（340000 AH）
福建省（350000 FJ）
江西省（360000 JX）
山东省（370000 SD）
河南省（410000 HA）
湖北省（420000 HB）
湖南省（430000 HN）
广东省（440000 GD）
广西壮族自治区（450000 GX）
海南省（460000 HI）
四川省（510000 SC）
贵州省（520000 GZ）
云南省（530000 YN）
西藏自治区（540000 XZ）
重庆市（500000 CQ）
陕西省（610000 SN）
甘肃省（620000 GS）
青海省（630000 QH）
宁夏回族自治区（640000 NX）
新疆维吾尔自治区（650000 XJ）
香港特别行政区（810000 HK）
澳门特别行政区（820000 Mo）
台湾省（830000 Tw）
扩展资料：
《县以下行政区划代码编制规则》是《中华人民共和国行政区划代码》的补充和拓延，它规定了表示乡、镇（街道办事处）一级行政区划的三位代码。
代码从左至右的含义是：
第一、二位表示省（自治区、直辖市、特别行政区）。
第三、四位表示市（地区、自治州、盟及国家直辖市所属市辖区和县的汇总码）。其中，01-20，51-70表示省直辖市；21-50表示地区（自治州、盟）。
第五、六位表示县（市辖区、县级市、旗）。01-18表示市辖区或地区（自治州、盟）辖县级市；21-80表示县（旗）；81-99表示省直辖县级市。
第七至九位表示乡、镇（街道办事处）
为了更详细地反映乡镇以下区划情况，国家统计局补充了三位表示居委会、村委会的代码。
《中华人民共和国宪法》规定，中国行政区划分为省级行政区、县级行政区、乡级行政区三个级别；
中国现行的行政区划实行如下：
一级省级行政区：分为省、自治区、直辖市、特别行政区；
二级地级行政区：分为地级市、〔地区行政公署管辖区域〕、自治州、〔盟行政公署管辖区域〕、直辖市〔仅台湾地区设置〕；
三级县级行政区：分为市辖区、县、自治县、县级市、旗、自治旗、林区、特区、〔特别行政区非政权性区〕。
四级乡级行政区：分为镇、乡、民族乡、〔街道办事处/地区办事处管辖区域〕、苏木、民族苏木、〔区公所管辖区域〕、县辖市〔仅台湾地区设置〕。
以省级行政区划分的结果如下：
华北地区：北京市、天津市、河北省、山西省、内蒙古自治区
东北地区：辽宁省、吉林省、黑龙江省
华东地区：上海市、江苏省、浙江省、安徽省、福建省、江西省、山东省、台湾省
华中地区：河南省、湖北省、湖南省
华南地区：广东省、广西壮族自治区、海南省、香港特别行政区、澳门特别行政区
西南地区：重庆市、四川省、贵州省、云南省、西藏自治区
西北地区：陕西省、甘肃省、青海省、宁夏回族自治区、新疆维吾尔自治区
淋巴癌是个什么？
别名“最会伪装的疾病”，淋巴瘤成为夺命杀手
据统计，全世界每9分钟就有1个淋巴瘤新发病例。我国淋巴瘤发病率为0.02‰，每年新增病人约2.5万人，死亡人数近2万，淋巴瘤的威胁正在迅速显现。它已跻身我国恶性肿瘤前十名，在血液系统恶性肿瘤里排名第二。该病初起时症状很隐匿，被形容为“最会伪装的疾病”。在洲际地区，非霍奇金淋巴瘤发生率远高于霍奇金氏病，大约为9：1，由于恶性程度更高、预后更差，所以一般谈到淋巴瘤就是指非霍奇金淋巴瘤。在我国，在恶性肿瘤发病率排名中，男性占第9位，女性占第10位。非霍奇金淋巴瘤可发生于各年龄阶段，高发年龄为45~60岁。其中，罗京患的是弥漫大B细胞淋巴瘤（简称DLBCL）。这是一种比较常见的非霍奇金淋巴瘤，属于侵袭性淋巴瘤，恶性度高，本病病程进展迅速，如不予以积极治疗，中位生存期不足一年。近些年来，淋巴瘤的研究和治疗都有了很大的进展，新药物新技术强势崛起！CAR-T疗法
其中以细胞免疫疗法中的嵌合抗原受体T（CAR-T）细胞疗法的表现尤为突出。它的出现代表了个性化癌症治疗的重大进步，特别是给血液系统恶性肿瘤患者带来重生的希望。完全缓解！国内首个接受CAR-T疗法的晚期淋巴瘤患者顺利出院！
虽然都是罹患弥漫大B细胞淋巴瘤，但是同病不同命，患有恶性淋巴瘤的陈先生就是一位幸运儿。据江苏公共·新闻频道《新闻空间站》报道：8月31日，国内首例使用CAR-T细胞治疗的淋巴瘤患者达到完全缓解，顺利出院。罗京吴宇森，同病不同命，对抗淋巴瘤，抗癌新势力CAR-T崛起
陈先生罹患的是弥漫大B细胞淋巴瘤，2010年10月份病发后，曾经接受过多次化疗，但都差强人意。弥漫大B细胞淋巴瘤是发病率最高的恶性淋巴瘤。采用免疫化疗后，60%左右的患者能够获得长期生存，但仍旧有40%的患者会复发。今年6月份，陈先生抱着尝试的态度，接受了CAR-T细胞疗法后，身体各项指标趋于正常。他欣喜地告诉记者，自己的身体状况比以前要好，出院后跟正常人无异。“活的药物”CAR-T疗法，让她完全缓解，展望没有癌症的未来
作为一种“活的”药物，CAR-T疗法与传统药物有着很大的区别。首先，该疗法需要从患者体内分离出T细胞，并在体外利用嵌合抗原受体（CAR）进行修饰，使其能够特异性识别癌细胞，最后再将改造后的T细胞扩增、回输至患者体内。与传统的化疗和造血干细胞移植相比，它对肿瘤细胞的杀伤更为精准，在提高疗效的同时大幅减轻了毒副作用。罗京吴宇森，同病不同命，对抗淋巴瘤，抗癌新势力CAR-T崛起
国内知名血液科主任介绍道：CAR-T能够非常特意地去识别淋巴瘤，肿瘤细胞上带有的抗原，接上之后就直接发动攻击，不需要第二信号再刺激，而产生一种抗肿瘤作用，直接把它杀灭，所以它的特点一个是精准，第二个是强大。适用的范围现在还是一般的免疫化学治疗无效的复发或者是难治的弥漫大B淋巴瘤。CAR-T疗法FDA获批6款，国内CAR-T疗法迎头赶上！
分享完上述关于CAR-T疗法治疗的新闻报道后，我们言归正传来聊下CAR-T疗法。目前，CAR-T疗法在血液系统恶性肿瘤的治疗中取得了重大成功。全球已有6款CAR-T细胞疗法在美国获FDA批准上市，2款CAR-T细胞疗法在中国上市。下图为国内外已上市的CAR-T细胞疗法。罗京吴宇森，同病不同命，对抗淋巴瘤，抗癌新势力CAR-T崛起
虽然我国CAR-T技术起步较晚，但国内市场规模大。根据 http://Clinicaltrials.gov 网站上的数据，中国成为2017年9月注册CAR-T试验最多的国家。截至2021年5月27日小编查询，全球总共有1301个CAR-T临床试验正在开展，中国注册的CAR-T试验的数量已达到478个！01 国内首款CAR-T疗法获批上市！中国迎来细胞免疫治疗元年
2021年6月22日，我国CAR-T领域的空白终于被打破！中国国家药品监督管理局（NMPA）最新公示，复星凯特生物科技有限公司（以下简称 “复星凯特”）靶向 CD19 的 CAR-T 细胞治疗产品阿基仑赛注射液（又称阿基仑赛，FKC876）正式获批上市。这是中国首个获批上市的CAR-T疗法，全球第6款获批上市的CAR-T疗法。相信紧随其后，中国将迎来CAR-T细胞疗法井喷时代。02 短短1个月，中国第2款、全球第6款CAR-T疗法获批！
2021年9月3日，国家药监管理局最新公示，药明巨诺靶向CD19的CAR-T产品瑞基奥仑赛注射液（relma-cel，商品名：倍诺达）已正式获批。瑞基奥仑赛注射液此次获批的适应症为：用于治疗经过二线或以上系统性治疗后成人患者的复发或难治性大B细胞淋巴瘤（r/r LBCL）。瑞基奥仑赛注射液是中国第二款获批的CAR-T产品，也是中国首款1类生物制品的CAR-T产品。罗京吴宇森，同病不同命，对抗淋巴瘤，抗癌新势力CAR-T崛起
距离上次7月30日提交审批，不过才短短1个月左右，可谓是进展神速，可喜可贺！复发？难治？太棘手！CAR-T疗法助外周T细胞淋巴瘤患者脱离治疗困境！mp.weixin.qq.com/s?__biz=MzI1NjE1NzMxOQ==&mid=2652354624&idx=2&sn=dc51d3bf81426fdb5b3e5784662fee79&chksm=f1c9eba8c6be62be1dea814dc550c49229e50a068b4c5eb8e690a7fbd0c36fa6d69c88d5d717&scene=21#wechat_redirect
爆！中国首款、全球第2款BCMA CAR-T疗法获FDA批准！
中国CAR-T细胞治疗行业中的“黑马”——传奇生物的靶向BCMA（B细胞成熟抗原）CAR-T疗法西达基奥仑赛（LCAR-B38M/JNJ-4528，下称cilta-cel）一直备受关注，已经在治疗多发性骨髓瘤的临床试验中表现出卓越的抗癌活性。令人振奋人心的是，当地时间2022年2月28日，由杨森公司（Janssen）和传奇生物合作开发的BCMA CAR-T产品西达基奥仑赛（商品名Carvykti），已获得美国FDA批准上市，用于治疗复发/难治性多发性骨髓瘤成人患者（MM）。这是中国首款获得FDA批准的细胞治疗产品，也是全球第二款获批靶向BCMA的CAR-T细胞免疫疗法。罗京吴宇森，同病不同命，对抗淋巴瘤，抗癌新势力CAR-T崛起
此前cilta-cel曾在5月26日被美国FDA授予优先审评资格，然而西达基奥仑赛的审批却遭遇延迟，由2021年11月29日调整至2022年2月28日，所幸最后终于获批，不负众望！cilta-cel是一种研究性B细胞成熟抗原（BCMA）导向的CAR-T疗法，用于治疗复发或难治性多发性骨髓瘤（RRMM）。这些患者在治疗前平均接受过5种前期疗法，76%的患者接受过5种治疗，86%的患者对5种疗法耐药，其中包括CD38治疗，而且对蛋白酶抑制剂PI和免疫调节剂IMiD双重耐药。简单说就是复发难治、后续缺乏有效的疗法。此款CAR-T疗法的原理与目前的PD-1/L1不同，它是直接利用患者体内的T细胞，将其在体外进行改造，大量复制后再会输到患者体内，以达到杀灭癌细胞的目的。在2021年的ASH会议上，1b/2期CARTITUDE-1研究（n=97）的最新结果显示，中位22个月的长期随访，客观缓解率（ORR）达到了98%，83%的患者达到严格的完全缓解（sCR），强调随着时间的推移缓解加深（sCR从2020年ASH年会上报告的67%增加到83%）。在18个月时，有66%的患者存活且疾病无进展。两年无进展生存率和总生存率分别为61%和74%。在2021年ASCO年会上将要公布的最新研究结果显示，中位随访18个月，总生存（OS）率为81%，缓解率在全部预先指定的亚组和不同治疗线数患者中具有可比性。美国研究显示cilta-cel长期疗效优异
其实早在2021年3月27日，FDA就批准了首款以BCMA为靶点的CAR-T疗法，用于接受过4种以上疗法后复发/难治性多发性骨髓瘤（r/r MM）成年患者。相关文章：突破！总缓解率高达98%，CAR-T疗法JNJ-4528有望拿下复发难治性肿瘤！mp.weixin.qq.com/s?__biz=MzI1NjE1NzMxOQ==&mid=2652355951&idx=2&sn=fdfb18a48850610e4e0c48ab3be640e8&chksm=f1c9ee87c6be67919da487e38f93016f01272af6fa0465f273bf7e52894d1942d8afcc47e75e&scene=21#wechat_redirect
28天免疫治疗后癌细胞清零，全球首例复发难治性淋巴瘤！CAR-T或是癌患新希望？mp.weixin.qq.com/s?__biz=MzI1NjE1NzMxOQ==&mid=2652362129&idx=2&sn=911811499fc9bd91d2bce19bc3c3fca7&chksm=f1c98679c6be0f6f1b50c5b4849d77e6df8ae3f1773cb7bedafe1351b5885b4c710b74a79b47&scene=21#wechat_redirect
惊喜！首例CAR-T治愈的多发性骨髓瘤患者生存超5年！
国外的Emily在2021年成功迎来了无癌生存的9年，俨然成为全球CAR-T疗法的“代言人”。在中国也存在这样一位被CAR-T疗法彻底改变了命运的幸运儿。闵先生在54岁被确诊患有一种特殊的罕见病——多发性骨髓瘤。家庭经济贫困的他当时没有药物可用，有幸参加了CAR-T疗法的临床试验。虽然治疗的过程不是一帆风顺的，但经过3次的治疗后，闵先生身上的包块全部消失，疼痛没有了。惊喜的是，截至2021年6月4日，闵先生无癌生活整整5年了，这才癌症治疗领域，就是理论上所说的临床治愈。罗京吴宇森，同病不同命，对抗淋巴瘤，抗癌新势力CAR-T崛起
目前，无癌家园有多款血液肿瘤及实体瘤的CAR-T临床试验正在进行研究中。罗京吴宇森，同病不同命，对抗淋巴瘤，抗癌新势力CAR-T崛起
精准爆破癌细胞的“生物导弹”ADC，强势加入淋巴瘤治疗队伍！
化疗抗癌，常常是“杀敌一千，自损八百”。抗体药物，能够精准找到肿瘤靶点，但有时候战斗力不足。要是能给抗体药物上安上化疗药物“弹头”，是不是就能更精准地打击癌细胞了？基于此，一种被称为“生物导弹”的ADC（抗体药物偶联物）横空出世。抗体偶联药物就像是生物导弹，由两部分核心功能组成：第一是抗体（导弹体），第二是强化疗药（核弹头）；这种设计会使抗体带着化疗药去找肿瘤细胞，然后精准地给肿瘤细胞下毒，毒死它们。这种药物设计结合了靶向药的精准和化疗药的高效，既避免了全身使用化疗药的毒副作用，也比单独使用靶向药具有更强的杀伤能力，一举两得。抗体偶联药物示意图注：（A）ADC结构的一般描述；（B）ADC的作用机制
全球已获批14款ADC药物，为后线患者带来延长生存期的希望
目前有100多种ADC正在进行临床试验。大多数ADC已从I期进展到 II 期。一些 ADC 的III期试验显示积极结果；截止2021年9月20日全球目前已有14款上市的ADC药物，治疗领域主要集中在血液瘤和实体瘤方面，并且主要是用于患者的后线治疗，包括晚期、复发/难治性以及转移性的肿瘤适应症。全球已获批14款ADC药物
从疗效数据来看，ADC药物给后线患者带了更多的治疗选择和延长生存期的希望，有多款药物的客观缓解率或中位无进展生存期相比化疗提高了一倍。CD30靶点面面观，F0002-ADC新药一炮而红，挤入淋巴瘤赛道
CD30是肿瘤坏死因子（TNF）受体超家族成员之一，可通过激活不同的信号通路促进细胞增殖或凋亡，2020年，注射用维布妥昔单抗（Adcetris）国内获批上市，CD30声名大噪。Adcetris作为一种靶向CD30的抗体偶联药物，对霍奇金淋巴瘤（HL）和间变性大细胞淋巴瘤(ALCL)有效率分别达到73%和86%，是近30年中在霍奇金淋巴瘤治疗领域首次获批的新药，也是首次以CD30位靶标的药物获批，填补了这一领域的空白。目前国内布局的关于CD30的ADC新药仅有F0002-ADC，这款新药由三部分组成，人鼠嵌合抗CD30单克隆抗体、硫醚连接子（MCC）和DM1，自2016年启动立项以来就身负众望！目前针对复发/难治性CD30阳性外周T细胞淋巴瘤患者正在临床招募中！这对于复发/难治性的外周T细胞淋巴瘤患者来说，又多了一条治疗的新选择！新免疫检查点抑制剂，为淋巴瘤患者提供新选择！
免疫疗法治疗癌症，与放化疗相比，具有更显著的抗癌效果及很小的副作用，例如现在很火的免疫检查点抑制剂PD-1/PD-L1抗体，不仅在实体瘤中占据一席之地，在复发难治性淋巴瘤方面也渐显其优势，地位不可撼动！与PD-1/PD-L1类似，CD47是肿瘤免疫治疗的新靶点。CD47也被称为整合素相关蛋白，表达于细胞的表面，肿瘤细胞更是出现了高表达。CD47可以与巨噬细胞表面的受体结合，向巨噬细胞释放"自己人，别吃我"的信号，抑制巨噬细胞的吞噬作用。抗CD47单克隆抗体对抑制肿瘤的生长和预防各种类型的癌症转移作用明显。淋巴瘤注射用IMM01书一款具有自主知识产权的新免疫检查点抑制剂，针对免疫调节靶点CD47，通过激活巨噬细胞对肿瘤细胞的吞噬作用，并将吞噬处理的肿瘤抗原递呈给T细胞，从而发挥强大的肿瘤免疫治疗效应。目前这款药物已经在中国、美国、日本获批发明专利。幸运的是，目前淋巴瘤注射用IMM01正在进行临床招募中，主要适应症为：经组织病理学确诊难治或复发性淋巴瘤患者1. 复发或难治性霍奇金淋巴瘤；2. 复发或难治性B细胞非霍奇金淋巴瘤；3. 复发或难治性NK/T细胞淋巴瘤；4. 复发或难治性急性髓系白血病；5. 复发或难治性骨髓增生异常综合征；6. 复发或难治性多发性骨髓瘤淋巴瘤并不可怕，治疗要“量体裁衣”
淋巴瘤并不可怕，是可以治好的。比如弥漫性大B淋巴瘤有50%以上可以治愈，也有一些类型淋巴瘤5年的生存率达70%~80%，霍奇金淋巴瘤的治愈率可达85%~90%。随着科学技术的发展，采用规范化的手段，以化疗+放疗+生物免疫治疗和生物靶向治疗的综合治疗手段，淋巴瘤的治疗目标已不再是缓解症状，而应是获得治愈。北京大学肿瘤医院的朱军教授认为，淋巴瘤的分型是否准确，首次治疗成功与否，决定疾病能否得到控制，也就是说第一次的治疗方案至关重要。但目前国内不少淋巴瘤患者首次治疗时未予充分重视，治不好了才找名医名院、用贵药治疗，结果反而引发耐药性。如果患者一开始就能在专科医生指导下，进行合理治疗，就有可能取得较好治疗效果，患者可以存活20年以上。当然，经过正规治疗后，肿瘤得到完全控制、临床完全缓解的患者，仍面临肿瘤复发的风险，特别是治疗后的1~2年，故定期随访复查必不可少，包括常规体检、血清学及影像学检查。患者前2年可每3个月复诊1次，后3年每半年复诊1次，如果不明原因出现症状，也应及时就诊。最后，小编要说一句，淋巴瘤并不可怕，要想预防淋巴瘤的发生，最重要的是要养成良好的生活习惯。保持乐观心态；学会劳逸结合，不要过度疲劳；还要注意饮食卫生，多吃绿色蔬菜与水果；最后，建议40岁以上的人群每半年或一年做1次健康体检。本文为无癌家园原创
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